Publications by authors named "Burak Dumludag"
Silymarin (Silybum marianum) has some protective effects against drug toxicity (cisplatin, acetaminophen, adriamycin, gentamicin etc.). Colistin is a strong antimicrobial, which is frequently used in the treatment of resistant gram-negative bacterial infections in recent years although it has nephrotoxic potential.
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- Dexpanthenol (Dexp) was investigated for its potential protective effects against contrast-induced nephropathy (CIN), a kidney injury caused by diagnostic procedures with contrast agents.
- In a study with rats, Dexp was administered before inducing CIN, and results showed significant improvements in kidney injury indicators and serum cystatin C levels, compared to those that only experienced CIN.
- Although Dexp did not significantly affect overall oxidative stress levels, it did alleviate some pathological damage associated with CIN, suggesting it may have benefits despite not addressing oxidative stress directly.
Introduction: Granulomatosis with polyangiitis (GPA) is a rare necrotizing vasculitis, which usually involves the upper and lower respiratory systems and kidneys and often have a relapsing course. Neutrophil/lymphocyte ratio (NLR) has been shown to be a useful marker predicting not only progressive disease, but also mortality in various inflammatory diseases. We aimed to investigate the roles of NLR in predicting the extend of clinical involvement and prognosis of patients with GPA.
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