Publications by authors named "Buonanno G"

The COVID-19 pandemic, caused by SARS-CoV-2, highlighted the importance of understanding transmission modes and implementing effective mitigation strategies. Recognizing airborne transmission as a primary route has reshaped public health measures, emphasizing the need to optimize indoor environments to reduce risks. Numerous tools have emerged to assess airborne infection risks in enclosed spaces, providing valuable resources for public health authorities, researchers, and the general public.

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Objective: To evaluate the impact of physical activity on the mood states of active and insufficiently active Italian adolescents and the relationships with sleep quality, sex, and academic performance, analyzing guidelines for the post-COVID-19 scenario.

Methods: This is a cross-sectional, quantitative, and descriptive study. Data collection was carried out through an electronic questionnaire via Google Forms.

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Article Synopsis
  • This study reviews the health impacts of using chlorine-based disinfectants versus other types in healthcare, particularly concerning infection control during filovirus outbreaks.
  • It includes data from 30 studies, focusing on risks related to respiratory issues linked to various disinfectants and application methods like spraying versus general disinfection tasks.
  • The findings show a significant association between chlorine exposure and respiratory problems, with spray methods posing a notably higher risk compared to other disinfecting techniques.
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The effect of cooking aerosol on the human heart was investigated in this study. The heart rate and blood pressure of 33 healthy adults were monitored before, exactly after, and two hours post-exposure (30 minutes, 60 minutes, 90 minutes, and 120 minutes after cooking). One hundred twenty grams of ground beef was fried in sunflower oil for twenty minutes using a gas stove without ventilation.

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Indoor air quality is negatively affected by the emission of different combustion sources releasing airborne particles and related particle-bound toxic compounds (e.g., heavy metals and polycyclic aromatic hydrocarbons).

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Emissions of ultrafine particles (UFPs; diameter < 100 nm) are strongly associated with traffic-related emissions and are a growing global concern in urban environments. The aim of this study was to investigate the variations of particle number concentration (PNC) with a diameter > 10 nm at nine stations and understand the major sources of UFP (primary vs. secondary) in Tehran megacity.

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The number of respiratory particles emitted during different respiratory activities is one of the main parameters affecting the airborne transmission of respiratory pathogens. Information on respiratory particle emission rates is mostly available for adults (few studies have investigated adolescents and children) and generally involves a limited number of subjects. In the present paper we attempted to reduce this knowledge gap by conducting an extensive experimental campaign to measure the emission of respiratory particles of more than 400 children aged 6 to 12 years while they pronounced a phonetically balanced word list at two different voice intensity levels ("speaking" and "loudly speaking").

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Public transport environments are thought to play a key role in the spread of SARS-CoV-2 worldwide. Indeed, high crowding indexes (i.e.

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Characterizing the size distribution of airborne particles carrying SARS-CoV-2 virus is essential for understanding and predicting airborne transmission and spreading of COVID-19 disease in hospitals as well as public and home indoor settings. Nonetheless, few data are currently available on virus-laden particle size distribution. Thus, the aim of this study is reporting the total concentrations and size distributions of SARS-CoV-2- genetic material in airborne particles sampled in hospital and home environments.

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The occurrence, long-range atmospheric transport and deposition of micro and nano plastics (MNPLs) remains un-quantified for the oceanic atmosphereopen ocean. Here we show the characterisation of MNPLs and the aerosol composition (PM) in a north-south Atlantic transect from Vigo (Spain) to Punta Arenas (Chile). The analytical procedure to assess the composition of MNPLs consisted of a double suspect screening approach of the polymers and additives, the two constituents of plastics.

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Atmospheric pollutants present environmental threats to health and have been investigated in different environments, such as highways, squares, parks, and gyms. These environments are frequented by older adults, who are considered fragile to the harmful impacts of pollution present in the air. The aim was to analyze the state of the art on the effects of air pollution on the health of older adults during physical activities (PAs) through a mapping review.

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Pathogens such as severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), influenza, and rhinoviruses are transmitted by airborne aerosol respiratory particles that are exhaled by infectious subjects. We have previously reported that the emission of aerosol particles increases on average 132-fold from rest to maximal endurance exercise. The aims of this study are to first measure aerosol particle emission during an isokinetic resistance exercise at 80% of the maximal voluntary contraction until exhaustion, second to compare aerosol particle emission during a typical spinning class session versus a three-set resistance training session.

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This is an account that should be heard of an important struggle: the struggle of a large group of experts who came together at the beginning of the COVID-19 pandemic to warn the world about the risk of airborne transmission and the consequences of ignoring it. We alerted the World Health Organization about the potential significance of the airborne transmission of SARS-CoV-2 and the urgent need to control it, but our concerns were dismissed. Here we describe how this happened and the consequences.

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Aim: Descending necrotising mediastinitis (DNM) is a rare but life-threatening condition. Diagnosis is challenging and prompt treatment is essential. We report a case of DNM in a 44-year-old man.

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Introduction: While increasing the ventilation rate is an important measure to remove inhalable virus-laden respiratory particles and lower the risk of infection, direct validation in schools with population-based studies is far from definitive.

Methods: We investigated the strength of association between ventilation and SARS-CoV-2 transmission reported among the students of Italy's Marche region in more than 10,000 classrooms, of which 316 were equipped with mechanical ventilation. We used ordinary and logistic regression models to explore the relative risk associated with the exposure of students in classrooms.

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Epidemiological studies investigating the association between daily particle exposure and health effects are frequently based on a single monitoring site located in an urban background. Using a central site in epidemiological time-series studies has been established based on the premises of low spatial variability of particles within the areas of interest and hence the adequacy of the central sites to monitor the exposure. This is true to a large extent in relation to larger particles (PM, PM) that are typically monitored and regulated.

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The infectious emission rate is a fundamental input parameter for airborne transmission risk assessment, but data are limited due to reliance on estimates from chance superspreading events. This study assesses the strength of a predictive estimation approach developed by the authors for SARS-CoV-2 and uses novel estimates to compare the contagiousness of respiratory pathogens. We applied the approach to SARS-CoV-1, SARS-CoV-2, MERS, measles virus, adenovirus, rhinovirus, coxsackievirus, seasonal influenza virus and (TB) and compared quanta emission rate (ER) estimates to literature values.

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Given that breathing is one of the most fundamental physiological functions, there is an urgent need to broaden our understanding of the fluid dynamics that governs it. There would be many benefits from doing so, including a better assessment of respiratory health, a basis for more precise delivery of pharmaceutical drugs for treatment, and the understanding and potential minimization of respiratory infection transmission. We review the physics of particle generation in the respiratory tract, the fate of these particles in the air on exhalation and the physics of particle inhalation.

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Article Synopsis
  • * Historically, diseases were believed to be transmitted through the air via miasma theory, but this changed with germ theory, which identified various other transmission methods over time.
  • * Recent research, particularly during the COVID-19 pandemic, has reaffirmed the importance of aerosol transmission, indicating that it could be a significant route for many respiratory infections, contrary to previous dominant beliefs.
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The spread of respiratory diseases via aerosol particles in indoor settings is of significant concern. The SARS-CoV-2 virus has been found to spread widely in confined enclosures like hotels, hospitals, cruise ships, prisons, and churches. Particles exhaled from a person indoors can remain suspended long enough for increasing the opportunity for particles to spread spatially.

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In this work, a novel technique is proposed that combines the Born iterative method, based on a quadratic programming approach, with convolutional neural networks to solve the ill-framed inverse problem coming from microwave imaging formulation in breast cancer detection. The aim is to accurately recover the permittivity of breast phantoms, these typically being strong dielectric scatterers, from the measured scattering data. Several tests were carried out, using a circular imaging configuration and breast models, to evaluate the performance of the proposed scheme, showing that the application of convolutional neural networks allows clinicians to considerably reduce the reconstruction time with an accuracy that exceeds 90% in all the performed validations.

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Plasmonic bio/chemical sensing based on optical fibers combined with molecularly imprinted nanoparticles (nanoMIPs), which are polymeric receptors prepared by a template-assisted synthesis, has been demonstrated as a powerful method to attain ultra-low detection limits, particularly when exploiting soft nanoMIPs, which are known to deform upon analyte binding. This work presents the development of a surface plasmon resonance (SPR) sensor in silica light-diffusing fibers (LDFs) functionalized with a specific nanoMIP receptor, entailed for the recognition of the protein human serum transferrin (HTR). Despite their great versatility, to date only SPR-LFDs functionalized with antibodies have been reported.

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