Publications by authors named "Buolikeze Kuoh Nji Geh"
Characterization of oral candidiasis according to antiretroviral treatment status, immunological and virological profiles among HIV infected patients in two health facilities in Yaoundé-Cameroon: a cross-sectional and analytical study.
Joseph Fokam Alex Durand Nka Ezechiel Ngoufack Jagni Semengue Cynthia Kelly Essono Asso'o Jeremiah Efakika Gabisa Buolikeze Kuoh Nji Geh
Pan Afr Med J
August 2023
Article Synopsis
- The study investigates the prevalence of oral candidiasis among people living with HIV (PLHIV) in Cameroon, differentiating between those on antiretroviral treatment (ART) and those who are ART-naive.
- Results show a significantly higher occurrence of oral candidiasis in ART-naive patients (27.7%) compared to ART-experienced patients (6.3%), indicating a strong link between ART use and decreased incidence.
- The findings highlight that immunodeficiency (CD4<200 cells/mm) and high viral loads (VL≥1000 copies/ml) contribute to the presence of oral candidiasis, emphasizing the need for management strategies for those experiencing immuno-virological failure.
Background: HIV infection is associated to different oral manifestations (including periodontal diseases), which have decreased with the advent of antiretroviral therapy (ART). Yet, the occurrence of periodontitis is still consistent among patients with HIV living in sub Saharan-Africa, with limited evidence on the driven factors and mitigating measures in these settings. We aimed at evaluating the occurrence of periodontitis and its associated immunological and virological factors in patients with HIV living in Yaoundé, Cameroon.
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