Synopsis of recent research by authors named "Bumhee Lim"
- Bumhee Lim's recent research focuses on innovative delivery systems for therapeutic compounds, specifically lipid nanoparticles for mRNA delivery and the development of inhibitors targeting oncogenic proteins and pathways in cancer treatments.
- In studies examining ferroptosis in lung cancer, Lim's work highlights the potential of chemical modifications of sorafenib to enhance its efficacy as an orally bioavailable agent, linking its mechanism to oxidative damage and system Xc inhibition.
- Lim also explores thiol-mediated cellular uptake mechanisms and potential inhibitors; his research on cyclic oligochalcogenides and cascade exchangers aims to enhance drug delivery efficiency and viral entry inhibition, showcasing the significance of dynamic covalent processes in drug design.
