Publications by authors named "Bum Sik Tae"
Article Synopsis
- The study investigates how polystyrene microplastics (PS-MPs) affect the reproductive health of male mice, focusing on potential mechanisms of damage linked to health issues like cancer and reproductive dysfunction.
- Thirty male mice were divided into groups and exposed to different doses of fluorescent PS-MPs for 28 and 56 days; tissues were analyzed for signs of inflammation, oxidative stress, and sperm quality.
- Results showed significant negative effects on sperm characteristics and elevated levels of certain inflammatory markers in testicular tissue, indicating that PS-MPs may harm male reproductive health through inflammatory responses.
Objectives: This study aims to share the experiences and outcomes of laparoscopic pneumovesical repair for vesicovaginal fistulas (VVF).
Materials And Methods: A retrospective review of medical records from a single institution over 10 years was conducted. The focus was on patients who underwent VVF repair using a pneumovesical approach with three 5 mm laparoscopic ports.
Introduction: This study investigated the learning curve of retrograde intrarenal surgery (RIRS) in patients with medium-sized stones using cumulative sum analysis (CUSUM) to evaluate the competence and proficiency of three new surgeons during their first RIRS procedures.
Materials And Methods: We conducted a retrospective review of 227 patients from 2019 to 2022 at a single institution. The patients were divided into four groups based on the operating surgeon: tutor surgeon (85 patients), newbie surgeon A (21 patients), newbie surgeon B (85 patients), and newbie surgeon C (36 patients).
Article Synopsis
- Patients with prostate cancer (PC) have an increased risk of depression, but this study examines how treatment methods (radiotherapy vs. surgery) influence that risk.
- The analysis used data from 210,924 Korean PC patients from 2007 to 2017, focusing on a final group of 9,456, revealing a slightly higher depression rate in those who received radiotherapy compared to those who had surgery.
- Ultimately, the study found no significant difference in the overall risk of depression between the two treatment groups, suggesting similar mental health outcomes regardless of the treatment method.
Article Synopsis
- The study aimed to analyze mumps and its complication, mumps orchitis, using the National Health Insurance Service Database in Korea.
- Data showed that 199,186 people were diagnosed with mumps, predominantly in males, with a noted increase in annual incidence and a lower risk in females.
- Mumps orchitis was the most common complication in males and indicates a need for more vaccinations, especially since it tends to affect adults during periodic outbreaks.
Article Synopsis
- - The study analyzed renal trauma incidence in South Korea from 2012 to 2016 using National Health Insurance Service Database data, revealing that out of 37,683 patients, 3.4% had high-grade trauma.
- - The findings showed a significant gender disparity, with a male to female ratio of approximately 3:1, and highlighted that certain age groups (41-60 and 61-80) and specific health conditions increased the risk of high-grade renal trauma.
- - Overall, the annual incidence was 17.33 per 100,000 population, with a gradual decline noted from 2013 to 2016, and most cases were treated conservatively, even among those with high-grade injuries
Purpose: The prevalence of catheter-associated urinary tract infections (CAUTIs) varies from 5% to 8.2%, and the risk of infection increases by 5% to 7% per day of primary indwelling. We investigated whether a novel biofilm inhibitory mechanism using an inhibitory silicone urethral catheter (a coated Foley catheter) can reduce CAUTIs compared to conventional non-coated Foley catheters.
View Article and Find Full Text PDFBladder cancers have high recurrence rates and are usually removed via transurethral resection of bladder tumor (TURBT). Recently, some reports showed that the anesthetic method may affect the recurrence rates of bladder cancers. The purpose of this population-based study was to compare the effect of anesthetic methods with the recurrence rates of bladder cancers in South Korea.
View Article and Find Full Text PDFPurpose: We aimed to analyze the characteristics and management of bladder and urethral injuries in Korea by use of the National Health Insurance Service (NHIS) database.
Materials And Methods: Data from the NHIS database representative of all cases of Korean bladder injury (n=4,631) and urethral injury (n=17,858) reported between 2012 and 2016 were analyzed. We used the International Classification of Diseases, 10th revision, clinical modification codes to identify the diagnoses.
Purpose: To evaluate the clinical impact of strict selection criteria for active surveillance (AS) of prostate cancer in a Korean population.
Materials And Methods: A single-center, prospectively collected AS cohort from December 2016 to February 2019 was used. Following pre-determined criteria, patients were categorized into "strict AS" and "non-strict AS" groups.
Herein, we review the assessment of quality-of-life (QoL) in radical cystectomy (RC) patients, summarize the result of studies for different surgical approaches, and provide an overview of patient management, as well as other considerations. In this review article, we reviewed the QoL research and research tools for patients undergoing RC, including urinary diversion methods, gender differences, and surgical methods (open surgery robotic surgery). This narrative review focused primarily on articles indexed in PubMed, Embase, Scopus, and Google Scholar databases.
View Article and Find Full Text PDFCognitive Function and Urologic Medications for Lower Urinary Tract Symptoms.
Int Neurourol J
September 2020
Special considerations should be made when selecting medications for the treatment of lower urinary tract symptoms (LUTS) in older patients especially those over 65 years old. This review summarizes the relationship between current treatments for LUTS and cognitive impairment. Although the recently reported association between dementia and tamsulosin is debatable, the effects of α-blockers and pharmacokinetics are not reported in this context.
View Article and Find Full Text PDFTreatment strategies for metastatic urothelial carcinoma (mUC) have evolved dramatically over the last decade. The emergence of immunotherapeutic agents, especially immune checkpoint inhibitors, has been the most significant development. Immunotherapy increased the overall survival rate of patients with mUC and provided a durable response.
View Article and Find Full Text PDFArticle Synopsis
- A clinical calculator for predicting 5-year mortality in patients with metastatic renal cell carcinoma (mRCC) was developed using data from the Korean Renal Cancer Study Group, involving 1,115 patients treated across several hospitals from 1993 to 2016.
- Key factors found to significantly increase mortality risk included high neutrophil-lymphocyte ratio, synchronous metastasis, and low levels of albumin and hemoglobin.
- The calculator showed good accuracy in predicting outcomes, and it can help patients and their families understand prognosis and determine the need for more intensive treatments.
Purpose: To evaluate the usefulness of natural killer cell activity (NKA) in diagnosing prostate cancer (PC).
Materials And Methods: The medical records of patients who underwent transrectal prostate biopsy (TRBx) at Korea University Ansan Hospital between May 2017 and December 2017 were retrospectively reviewed. NKA levels were measured using NK VueR Tubes (ATgen, Sungnam, Korea).
Purpose: To evaluate if preoperative sterile pyuria can be a prognostic factor for intravesical recurrence (IVR) and overall survival (OS)in patients with upper tract urothelial carcinoma (UTUC) undergoing surgery.
Materials And Methods: We retrospectively reviewed the medical records of patients who were diagnosed with UTUC from October 2003 to December 2016 at Korea University Medical Center. Sterile pyuria was defined as urine containing five or more white blood cells per high-power field in the absence of bacteria in urine culture.
Purpose: To evaluate seasonal variations of overactive bladder (OAB) symptoms in women who visited hospital clinics.
Methods: Medical records of female patients treated for OAB symptoms from January 2011 to December 2017 were retrospectively reviewed. Patients with pyuria at the first visit, those who did not complete the questionnaire, and those with <3 overactive bladder symptom scores (OABSS) were excluded.
Background: E-cadherin has emerged as a prognostic factor of urothelial cell carcinoma. In the present work we investigate the relationship between expression of E-cadherin and clinical outcomes, following radical nephroureterectomy for upper tract urothelial cell carcinoma.
Methods: We systematically searched PubMed, Embase, Cochrane Library, and Web of Science databases to identify eligible studies published until July 2017.
The aim of this study was to evaluate whether balneotherapy might be effective in patients with chronic pelvic pain (CPP) in the short term. This was an open and prospective pilot study. The balneotherapy programme was performed in a spa resort located in Wando Island, Republic of Korea from August 26 2018 to September 1 2018.
View Article and Find Full Text PDFPurpose: To establish a prospective, comprehensive, multidisciplinary, bio-bank linked genitourinary cancer cohort based on standard real practice.
Materials And Methods: We established the Seoul National University Prospectively Enrolled Registry for Genitourinary Cancer (SUPER-GUC), a prospective cohort clinical database and bio-specimen repository system for prostate cancer (SUPER-PC), renal cell carcinoma (SUPER-RCC), and urothelial cancer (SUPER-UC) at a high-volume, tertiary institution. Each cohort consists of several sub-cohorts based on treatment or disease status.
Purpose: Previous studies have suggested that androgen deprivation therapy (ADT) is associated with cerebral infarction. However, conflicting results have been reported by other researchers. The aim of this study was to evaluate the association between ADT and cerebral infarction in patients with prostate cancer (PC) using big data.
View Article and Find Full Text PDFBackground: Potency preservation often does not meet expectation despite nerve-sparing prostatectomy.
Objective: To set the protocol for intraoperative cavernous nerve monitoring and mapping during robot-assisted radical prostatectomy (RARP), and to evaluate its safety and clinical feasibility.
Design, Setting, And Participants: A prospective phase I/II, feasibility study was performed.
Purpose: To describe our initial experience with a novel method of adenoma retrieval using a pneumovesicum (PNV) after Holmium laser enucleation of the prostate (HoLEP).
Methods: From January 2016 to April 2018, a total of 93 consecutive patients treated with HoLEP were enrolled in this study. For tissue morcellation, we used the PNV morcellation technique for an initial series of 21 patients and the conventional technique (Lumenis VersaCut) for a consecutive series of 72 patients.