Barriers and facilitators to implementing polypharmacy management frameworks: a theory based qualitative exploration of key stakeholders.

Background: Inappropriate polypharmacy arises through many factors including deficiencies in prescribing processes. Most research has focused on solutions at the clinician/patient levels with less at the organisational level.

Aim: To explore key stakeholder identified barriers and facilitators to implementation of an organisational level polypharmacy management framework.

Effectiveness of Mediterranean Diet on Daytime Sleepiness among Individuals with Type 2 Diabetes Mellitus in Oman.

 Sleep disturbance is a major complaint among individuals with diabetes mellitus and may be augmented by dietary interventions. The objective of this randomized controlled trial was to determine the effectiveness of a Mediterranean diet intervention on daytime sleepiness among individuals with type 2 diabetes mellitus (T2DM) in Oman.  In total, 134 eligible individuals with T2DM (61 and 73 participants in the intervention and control groups, respectively) were recruited.

Effect of Supplementation on Reproductive Parameters of Sahrawi and Jabbali Goat Bucks.

Spirulina platensis (SP) is a protein-rich dietary supplement that improves animal reproductive traits. This study investigated the effect of SP supplementation on puberty onset, semen characteristics, scrotal circumference (SC), libido, and hormone concentrations in Sahrawi and Jabbali bucks. The study was conducted in 36 bucks, divided into three groups ( = 6/group), for 70 days.

Implementation frameworks for polypharmacy management within healthcare organisations: a scoping review.

Background: Several guidelines support polypharmacy management in individual patients. More organisational-level focus is needed on the use of implementation frameworks.

Aim: To characterise the peer reviewed literature on implementation frameworks, focussing on barriers and facilitators to implementation at organisational level in the context of polypharmacy management.

The Impact of Demographic, Clinical Characteristics and the Various COVID-19 Variant Types on All-Cause Mortality: A Case-Series Retrospective Study.

(1) Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly evolved into a pandemic affecting virtually every country in the world. We evaluated the demographic, clinical, laboratory, and all-cause mortality of moderate and severe COVID-19 patients admitted to a tertiary care hospital in Oman during the different COVID-19 waves and variant types. (2) Methods: A case-series retrospective study was carried out between 12 March 2020 and 30 June 2022.

Edible bird's nest supplementation in chilled and cryopreserved Arabian stallion semen.

Diluents and various biological products have been used in different animal species, with promising outcomes in post-thaw sperm quality. Nevertheless, only a few reports are available for the semen of Arabian horses. Edible bird's nest (EBN) - a product of the salivary secretions of swiftlet species is widely known to have both antioxidant and anti-inflammatory properties.

Effect of advancing the breeding season on reproductive performance of dromedary camels.

This study examines the effect of advancing the breeding season on the reproductive performance of dromedary camels under an intensive management system. Using a synchronization protocol, timed natural mating in female camels was carried out either in September (2 months ahead of the natural breeding season, n = 182) or December (peak breeding season, n = 115). The ovarian responses (size of the dominant follicle at the time of mating and ovulation), pregnancy rate, and pregnancy losses were evaluated using ultrasonography.

Investigation of some trace elements and hematological and biochemical parameters in the blood of emaciated Omani goats.

Background And Aim: The analysis of hematological and biochemical parameters is widely used in assessing animal health status. Limited information is available on trace element levels and their association with hematological and biochemical parameters in Omani goats suffering from emaciation. Therefore, the current study aimed to determine the levels of some trace elements in emaciated Omani goats and their relationship with hematological and biochemical parameters.

A preliminary study on the effects of E-Z Mixin® and EquiPlus® extenders supplemented with Edible Bird's Nest on the quality of chilled Arabian stallion semen.

The aim of this study was to evaluate the effects of adding different concentrations of edible bird's nest (EBN) which is secreted by swiftlet birds (), into EquiPlus® and E-Z Mixin® extenders on the quality of chilled Arabian stallion semen at various storage times (0, 24 and 48 h). Ten ejaculates were collected from five stallions, and diluted using the two extenders containing 0% (control), 0.12%, 0.

Superovulation of dromedary camels with eCG: An effective and practical technique.

This study was conducted to develop simple superovulation protocols for dromedary camels using eCG. In experiment 1, camels received either 1000, 2000, 3000, 4000, 5000 or 6000 IU eCG. In experiment 2, camels received either 400 mg FSH (Folltropin-V) twice-daily over 5 days or 3000 IU eCG.

Artificial insemination with fresh, liquid stored and frozen thawed semen in dromedary camels.

This study was conducted to evaluate various factors affecting fertility following insemination of dromedary camels. In experiment 1, camels were either bred by natural mating (NM) or inseminated in the body of uterus with whole, split (50:50) or 1 mL of undiluted ejaculate. In experiment 2, camels were inseminated with fresh diluted semen either in the body of the uterus or tip of the uterine horn and at either the time of ovulation induction (0 h), 24 or 30 h later.

Liquid storage of dromedary camel semen in different extenders.

This study was conducted to assess the effects of commercial extenders and storage temperature on dromedary camel sperm quality during liquid preservation. In Experiment 1, ejaculates (n = five males; replicated seven times) were split and diluted with synthetic (OPTIXcell, EquiPlus, INRA96, Bioxcell or AndroMed; Experiment 1a) or egg-yolk based (Biladyl, Green buffer or Triladyl; Experiment 1b) extenders and stored for 48 h at 4 °C. In Experiment 2, split ejaculates (n = five males; replicated six times) were used to directly compare Green buffer, OPTIXcell and Triladyl extenders over 48 h of storage at 4 °C.

Reproductive seasonality of male dromedary camels.

Reproductive seasonality has been reported in numerous species, including male dromedary camels, yet investigations into seasonal changes in camel semen quality have yet to be conducted. The aim of this study was to characterise the seasonal changes in camel semen quantity and quality as well as correlate these changes to testis and accessory sex gland morphology, sexual behaviour, libido and environmental factors such as day length and ambient temperature in Oman. Semen was collected twice a month for a year and testicular and accessory sex organ biometry recorded once a month via ultrasonography (n = 8 bulls).

Simplified superovulation protocols in dromedary camels (Camelus dromedarius).

This study was conducted to develop simple superovulation protocols in dromedary camels. Using two commercial FSH products, a series of experiments was conducted to evaluate the effect of different superovulation protocols on ovarian response and embryo production. In experiment 1, camels in control group (n = 15) received 400 mg Folltropin-V in a traditional protocol (FSH diluted in saline and given twice daily in decreasing doses over 5 days) and camels in split-injection (2 doses 48 h apart) groups received either 400 (n = 16, first dose: 320 mg, second dose: 80 mg) or 200 mg (n = 16, first dose: 120 mg, second dose: 80 mg) of slow-release (SR) preparation of Folltropin-V [Folltropin-V diluted in hyaluronan (5 mg/mL) solution].

Effect of semen collection frequency on the semen characteristics of dromedary camels.

The effect of semen collection frequency (once or twice per week) on the sexual behaviour, libido and semen characteristics (volume, colour, gross activity, viscosity, sperm concentration, morphology, motion characteristics and membrane viability and acrosome integrity) of dromedary camels (n = 7) was investigated over the course of 8 weeks. Results showed that frequency of collection influenced male camel libido (P < 0.05) but not sexual behaviour.

The Characteristics and Outcomes of Patients Who Make an Emergency Department Visit for Hypertension After Use of a Home or Pharmacy Blood Pressure Device.

Study Objective: Emergency department (ED) visits for hypertension are rapidly increasing. Hypertension guidelines began recommending use of self-measurement blood pressure (BP) devices in the early 2000s, which could be contributing to the increase. We aim to examine the proportion of ED visits for hypertension that occurred after a BP measurement with a self-measuring device, and the associated outcomes.

Resynchronization of synchronized follicular wave in dromedary camels of unknown pregnancy status (Camelus dromedarius).

This study was designed to evaluate the use of resynchronization (Resynch) protocol in dromedary camels. In experiment 1, the effect of initiation of Resynch protocol with GnRH treatment on Day 14 ± 2 after timed breeding (TB) in camels of unknown pregnancy status on pre-established pregnancy and resynchronized fertility, was examined. The camels (n = 201) were divided into two groups after synchronized TB.

Evaluation of wet cupping therapy on the arterial and venous blood parameters in healthy Arabian horses.

Aim: Recently, the complementary therapies such as cupping and acupuncture are being used in veterinary medicine. This research was carried out to determine the effects of wet cupping therapy (Hijama) on the hematological and the biochemical parameters in the healthy Arabian horses for the first time.

Materials And Methods: In this study, seven clinically healthy Arabian horses were randomly selected.

Biochemical analysis of some serum trace elements in donkeys and horses in Eastern region of Kingdom of Saudi Arabia.

Aim: Little is known about the serum levels of trace elements in donkeys and horses in Saudi Arabia. This study aimed to investigate the levels of some trace elements in these two species in the eastern region of Saudi Arabia and to compare the obtained results with the reference values.

Materials And Methods: Seventeen Arabian horses and twenty eight Hassawi donkeys were randomly selected for this study.

Some hematological and biochemical parameters of different goat breeds in Sultanate of Oman "A preliminary study".

Aim: In Sultanate of Oman, goats are considered as one of the most important livestock in which there are many breeds of goat such as Batinah, Jabali, Dhofari, Jabal Al-Akhdar, Sahrawi, and Sahrawi Musandam. Little hematological and biochemical information is known on Omani goat breeds; therefore, the main purpose of this study was to determine reference baseline data regarding hematological and biochemical values of different Omani goat breeds.

Materials And Methods: A total of 30 healthy animals of different Omani goat breeds (Jabali, Jabal Al-Akhdar, Sahrawi, and Sahrawi Musandam) were selected randomly from different areas in Sultanate of Oman.

Characterization of ovulatory capacity development in the dominant follicle of dromedary camels (Camelus dromedarius).

The acquisition of ovulatory capacity in the growing dominant follicle (DF) of dromedary camels was examined in the current study. Ovulation occurred in response to hCG (1500 IU) in 27.3%, 58.

Synchronisation of the follicular wave with GnRH and PGF2α analogue for a timed breeding programme in dromedary camels (Camelus dromedarius).

This study was conducted to develop a hormone protocol that precisely synchronises follicular development for a timed breeding (TB) programme in dromedary camels. To examine the effect of GnRH treatment at four known stages of follicular development, animals were treated with GnRH when the largest follicle of the wave was 4-7, 8-11, 12-17 and 18-27 mm in diameter. Transrectal ultrasonography was carried out daily up to 20 days after treatment.

Ultrasonographic characterization of follicle deviation in follicular waves with single dominant and codominant follicles in dromedary camels (Camelus dromedarius).

Follicular wave emergence was synchronized by treating camels with GnRH when a dominant follicle (DF) was present in the ovaries. Animals were scanned twice a day from day 0 (day of GnRH treatment) to day 10, to characterize emergence and deviation of follicles during the development of the follicular wave. Follicle deviation in individual animals was determined by graphical method.

Characterization of ovarian follicular dynamics in dromedary camels (Camelus dromedarius).

Ovarian follicular dynamics was monitored by transrectal ultrasonography, for a period of 60 to 90 days, and its correlation with plasma estradiol-17β (E2) and progesterone (P4) were studied in seventeen, multiparous, non-lactating, 12 to 20-year-old dromedary camels. The average number of follicles recruited (12.77 ± 0.

Effect of progesterone from induced corpus luteum on the characteristics of a dominant follicle in dromedary camels (Camelus dromedarius).

The present study was carried out to elucidate the effect of progesterone (P4) from the induced corpus luteum (CL) on the characteristics of the dominant follicle (DF) in dromedary camels (Camelus dromedarius). Ovarian follicular and induced CL dynamics were monitored by transrectal ultrasonography in eight camels during the peak breeding season. The characteristics of the DF were monitored daily from the day of emergence into a wave, until it appeared to lose its dominance and the DF of a subsequent wave grew to a diameter of 13-17 mm.