[Muscle regeneration and the state of the thymus in adult rats under laser irradiation and alloplasty of the gastrocnemius muscles and diaphragm of newborn rats].

The regeneration of gastrocnemius muscles of adult rats under implantation conditions in areas of muscle tissue damage in newborn rats has been studied. Alloplasty was performed using minced gastrocnemius and diaphragm muscles, which differs at birth in animals by degree of differentiation. The rat-recipient area of alloplasty was subjected to He-Ne laser radiation before operation, with the aim of reducing the immune response to allogenic muscle tissue.

[Morphofunctional characteristics of the thymus and the muscle regenerating under laser irradiation and alloplasty of the adult muscle tissue in the trauma region].

The effect of muscle tissue alloplasty and He-Ne laser radiation on the skeletal muscle regeneration and thymus function was studied. Allogenic muscle tissue was implanted from an adult rat. Without laser irradiation (the first series of experiments), initial enhancement of thymus recovery observed on day 7 after alloplasty (a characteristic stress response to operation) was followed by gradual destructive changes in the thymus tissue.

[Regenerative activity of muscle tissue and thymus status in young and old mdx mice with muscle injury and wound xenoplasty].

Responses of the skeletal muscle tissue and thymus to muscle injury (complete transection) and wound xenoplasty with the minced muscle tissue of newborn rats (tissue therapy) were studied in mdx mice aged 12-16 and 40-48 weeks. The muscle tissue of mdx mice has genetic defects causing chronic dystrophic processes in it. The muscle tissue of young mdx mice proved to retain a relatively high capacity for regeneration.

[Structure peculiarities of muscle regenerates and state of thymus under He-Ne laser therapy in different periods after muscle trauma].

We studied the gastrocnemius muscle regeneration and the reactive changes in thymus of rats under different regimens of He-Ne laser therapy of both operated legs (632.8 nm; 2.5-3.

[Plasticity of allogenic muscle tissue transplanted into a traumatized rat muscle subjected He-Ne laser radiation].

The effect of muscle tissue alloplasty and laser radiation on the post-traumatic regeneration of skeletal muscles was studied. The implantation of an unirradiated minced allogenic muscle tissue into the area of trauma of a previously laser-irradiated muscle had a positive effect. The allogenic muscle tissue underwent active regeneration.

[Regenerative capacity of muscle tissue and thymus state in irradiated rats exposed to long-term He-Ne laser radiation].

We studied the effect of He-Ne laser on regeneration of damaged gastrocnemius muscle in rats irradiated at 6 Gy in conditions of fractional laser energy spread (10 exposures, 3 min for each limb, within 30 days after the operation; 2-3 exposures weekly; 2.5-3.0 mW/cm2 power density; and 9.

[Regenerative activity of muscle allografts and thymus status during long-term laser exposure of adrenals and homoplasty region prior to transplantation].

Cross allografting of both gastrocnemius muscles between intact rats and those with the adrenal and right shin preirradiated with a He-Ne laser (632.8 nm, 2.5-3.

[Structure and functions of muscle allotransplants developing in adrenals and the alloplasty area after long-term exposure].

The cross allotransplantation of right gastrocnemius muscles was carried out between intact rats and rats in which adrenals and right shins were subjected to low-energy He-Ne laser radiation (10 procedures for 2 weeks, the exposure duration 5 min; total dose for each rat 15-18 J/cm2). By conditions of experiment, the rats in each series were both donors and recipients, and hence the heterogeneity of rats in each series was the same. It was shown that the laser radiation in the dose studied and the regimes of exposure of rat adrenals and shin (area of the planned allotransplantation) influenced the muscle alloplasty.

[Histogenetic, metabolic, and immunologic aspects of the effect of infrared laser radiation on injured skeletal muscles from irradiated and nonirradiated rats].

Using biochemical, histological, morphometric and cytogenetic methods, it was shown that low-intensive infrared laser radiation (total dose 3.6 J/cm2), applied to the injured rat skeletal muscles, stimulated metabolism and regeneration more efficiently in the muscles locally exposed to 20 Gy X-rays compared to the unexposed muscles. The laser irradiation promoted postradiative recovery in bone marrow cells, but did not provide normalization in thymus lymphocyte activity.

[Regeneration of gastrocnemius muscle and state of immune system in radiated rats under the influence of He-Ne laser].

We studied the influence of a low-energy He-Ne laser on the regeneration of the transected gastrocnemius muscle and state of the thymus and bone marrow in adult mongrel rats irradiated at 6 Gy using the histological, morphometric, and cytogenetic methods. The laser influence on both rat hind limbs (at total doses of 9.0-10.

[Experimental study of the effect of pulsed infrared laser radiation on skeletal muscle regeneration after mechanical trauma].

Impulse infrared laser radiation (0.89 microm) was examined for effect on regeneration of cross-cut musculus gastrocnemius in adult rats (ten 3-min exposures, 2-3 procedures weekly for one month after the operation, modulating frequency 10 Hz, total course dose 3.6 J/cm2).

[Structural and functional characteristics of muscle allotransplants, formed under different conditions of laser irradiation].

It is known that a low-energy laser radiation can cause reflex suppression of immunity. The present experiments were designed to determine the plastic activity of allogenic muscle tissue in different conditions of a previous action of laser rays. The cross homotransplantation of gastrocnemius muscles was carried out between intact rats, or between rats in which 14 days before transplantation each hind leg was subjected to low-energy He-Ne laser radiation in dose of 7.

[A comparative analysis of the action of red and infrared laser radiation and ultrasound on the regeneration of locally irradiated skeletal muscle and on immune system function in the rat].

The study was made of a regeneration ability of the rat skeletal muscle which had been mechanically injured and exposed to a 20 Gy irradiation, of the thymus and bone marrow condition after local exposure of the muscle to red and infrared laser radiation and ultrasound. These factors were found to stimulate regeneration of the injured soft tissues and to reduce cytogenetic damage to bone marrow cells in the irradiated zone under growing immunosuppression. The stimulation was most potent in prolonged exposure to the ultrasound.