Synchronous right nephrectomy, left kindey tumorectomy, right lateral hepatic sectorectomy and inferior vena cava thrombectomy for metastastic clear cell renal carcinoma. Report of a case and review of the literature.

The prognosis of stage IV renal cell carcinoma is very poor, since non-operative modalities for advanced renal carcinoma have failed to yield effective results. In fact, there is no indication for radiotherapy and systemic chemotherapy is not effective. Surgery, when indicated, seems to be the only therapeutic option possible.

Synchronous nephrectomy and right hepatectomy for metastatic chromophobe renal cell carcinoma: report of a case and review of the literature.

The prognosis of metastatic renal cell carcinoma is poor, since non-operative modalities for advanced renal carcinoma have failed to yield effective results. In fact, there is no indication for radiotherapy, except for palliative treatment of symptomatic bone metastases, and systemic chemotherapy is not effective. Despite the promising early results with immunotherapy, a complete response occurs in less than 15% of patients and is rarely lasting.

Combined percutaneous-transurethral incision for treatment of ureterocele in adults.

We report our experience with a combined percutaneous-transurethral endoscopic incision in the treatment of ureterocele in 15 adult patients, a technique that enhances accuracy and has been associated with excellent functional results.

Gemcitabine plus mitoxantrone and prednisone in the palliative treatment of hormone-resistant prostate cancer (HRPC): A phase II study (GOAM 01.01 study).

Background: The present exploratory phase II study was performed to evaluate the activity and tolerability of adding a second agent (gemcitabine) to the well-tolerated mitoxantrone/prednisone regimen in patients with locally advanced or metastatic prostate cancer no longer responsive to hormonal treatment.

Patients And Methods: Forty-three patients with hormone-refractory prostate cancer (HRPC) were included in the study from May 2000 to April 2004. Their median age was 71 years (range, 56-81) and their median Karnofsky performance status (KPS) was 90 (range, 70-100).

[Our experience in urologic surgery with a new polyglycolic acid (Darvin)].

Catgut chromic has long been used as an absorbable suture and recently polyglycolic acid has been used widely as a suturing material causing minor tissue reaction. The aim of this study is to consider the bioavailability of a new absorbable suture which is a modified polyglycolic acid: Darvin. We considered 10 consecutive patients surgically treated for a bladder disease.

Endourologic procedures for ureteropelvic junction stenosis: techniques and results.

Twenty-two cases of stenosis of the ureteropelvic junction were treated by endourologic procedures; 13 were associated with renal stones. Three techniques were used, depending on the type and degree of obstruction: (1) anterograde or retrograde dilation with a double-lumen balloon dilator catheter; (2) incision of the stricture with a cold knife after a percutaneous approach to the kidney; and (3) incision of the stenosis with a new flexible knife through a nephrostomy tract. Balloon dilation was always performed after the incision.

Clinical experience with low dosage of propionohydroxamic acid (PHA) in infected renal stones.

The use of drugs inhibiting bacterial urease represents an interesting improvement in preventive treatment of renal infected stones. The low dose (120 mg/day) for one week followed by 60 mg/day of propionohydroxamic acid (PHA) has shown excellent anti-urease activity. The nearly normal absence of side effects also allows long-term administration.

[Radiological aspects and results of percutaneous ultrasonic nephrolithotripsy].

Percutaneous removal of renal stones is becoming an established procedure, especially for stones lying free in the renal pelvis. These techniques, which include: retrograde pyelography to facilitate a thorough understanding of caliceal anatomy and stone position in 3 dimensions; approaches for accurate placement of a nephrostomy tract for straightline access to the stone and stone removal are discussed.

[Crystalluria during prophylactic treatment of urinary lithiasis with allopurinol, hydrochlorothiazide, manganese oxide, diphosphonates and propionohydroxamic acid].

The study of cristalluria was used as a method to evaluate the severity of nephrolithiasis and the efficacy of different drug therapies. The number and dimensions of urinary crystals as well as the number of crystal aggregates, were determined in patients with infected calcium or uric acid nephrolithiasis. Crystalluria was studied before therapy and at 6 and 12 months during treatment.

Acetohydroxamic acid therapy in infected renal stones.

The use of acetohydroxamic acid at different dosages is recommended in the treatment of renal lithiasis secondary to urease-producing bacteria. The effects of this drug are directed to urinary ammonium and urinary pH reduction and to potentiation of antibiotic therapy.

Urease inhibitor therapy in infected renal stones.

The strict dependence of struvite and carbonate apatite renal stones on the urease-producing germs confirm the need to combine bacterial urease inhibitor drugs with antibiotic treatment. Of the two antiurease drugs used the better results were obtained with acetohydroxamic acid, both for its minimum side effects and its more powerful urease-inhibitor capacity. Thus stone recurrence was avoided even in patients with urinary infection not responding to specific antibiotic treatment.

Post-transplantation ureteral stricture: controlateral pyelocalicostomy.

An extensive ureteral stricture developed in a patient 10 years after a renal transplantation. A normal controlateral collecting system has been used for a pyelocalicostomy with excellent postoperative result.