The analysis of immunophenotype of gastrin-producing tumors of the pancreas and gastrointestinal tract.

Background: Gastrinomas are located more frequently in the pancreas, which normally has no cells that can produce gastrin. They have a more aggressive course than other pancreatic endocrine tumors and extrapancreatic gastrinomas associated with multiple endocrine neoplasia Type 1 syndrome. The current study analyzed immunophenotypes of gastrinomas and compared them with other pancreatic endocrine tumors.

[Surgical treatment of duodenal ulcer in elderly and aged patients].

Choice of treatment of duodenal ulcer in elderly and aged patients is discussed. Literature demonstrate high risk of recurrences even in adequate systemic drug treatment. In patients of this age group early organo-saving operations must be performed before development of complications.

[Current problems of the surgical treatment of uncomplicated duodenal ulcer].

How to choose treatments for uncomplicated duodenal peptic ulcer is discussed. The data available in the literature suggest that there is a high incidence of recurrent ulcers even after regular. This is evidenced by experience in examining and treating 1414 patients at the Institute of Surgery.

[Selective proximal vagotomy and duodenoplasty in surgical treatment of stenotic duodenal ulcer].

Experience in the treatment of 70 patients with stenotic duodenal ulcer by surgery is generalized. In addition to SPV the patients underwent duodenoplasty as a draining operation. There were 61 (87.

[Surgical treatment of hormone-induced recurrent and peptic ulcers of anastomosis].

The authors operated on 20 patients with the Zollinger-Ellison syndrome and on 3 patients with Wermer's syndrome. The clinical picture of the disease and the findings of laboratory tests and special methods of examination allow the Zollinger-Ellison syndrome to be diagnosed in most cases and a niveau diagnosis of gastrinoma to be established in some cases. Intraoperative ultrasonic examination is significant in making the niveau diagnosis.

[Dumping syndrome after selective proximal vagotomy].

An analysis of causes of the development of dumping-syndrome after selective proximal vagotomy (SPV) has been made. Dumping-syndrome most frequently developed after SPV with draining operation (12.9%).

[Pharmacokinetics of ampicillin in patients with gastric and duodenal ulcers and patients having undergone Billroth II gastric resection].

It has been shown that exacerbation of gastric and duodenal ulcers results in a more complete absorption of ampicillin administered per os. Pyloric stenosis retarded ampicillin absorption. Billroth II stomach resection does not change the drug kinetics in the blood.