Publications by authors named "Bukania Z"

Proper nutrition is vital for maintaining good health for all people across their lifespan, especially children and mothers, who are especially vulnerable due to their specific nutrient needs. Despite the necessity of improved nutrition for these groups, some members do not fully meet their recommended daily micronutrient needs, a challenge exacerbated by different socioeconomic, cultural, and communal constraints resulting in malnutrition. Iron deficiency anaemia is a major concern among children and mothers, especially in pastoralist communities, due to poor nutrition and other related factors.

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  • - The study explores men's unique barriers to accessing healthcare services under Universal Health Coverage (UHC) in Kenya, highlighting socio-cultural and economic factors that influence their healthcare-seeking behaviors.
  • - Through 30 focus group discussions with 296 men across 12 counties, three main themes emerged regarding men's perspectives: experiences with healthcare access, the impact of socio-cultural beliefs, and their desires for healthcare systems.
  • - Findings indicate that issues such as masculinity norms, financial constraints, lack of male-friendly services, and limited health literacy create a disconnect between men's needs and the current healthcare system, complicating their ability to receive necessary care.
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Many statistical models have been proposed in the literature for the analysis of longitudinal data. One may propose to model two or more correlated longitudinal processes simultaneously, with a goal of understanding their association over time. Joint modeling is then required to carefully study the association structure among the outcomes as well as drawing joint inferences about the different outcomes.

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  • Kenya is struggling with health worker shortages and uneven distribution of healthcare resources, prompting the Ministry of Health to set standards for healthcare providers and infrastructure.
  • A study was conducted to evaluate the effects of Universal Health Coverage (UHC) pilot programs on Human Resource for Health (HRH) using a mix of quantitative and qualitative methods across different counties.
  • Data collection involved a detailed assessment of available healthcare resources and staff at health facilities using specific tools, with findings analyzed statistically to compare UHC pilot counties with non-UHC ones.
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  • - Cross-over designs in clinical trials allow researchers to compare treatments within the same subjects, providing more precise estimates of efficacy, especially for new drugs.
  • - A recent study analyzed a new piecewise linear mixed-effects (PLME) model against traditional models—Grizzle's mixed-effects (GME) and Jones & Kenward's mixed-effects (JKME)—to evaluate their performance in analyzing cross-over trial data.
  • - Results indicated that the PLME model outperformed the GME and JKME models in estimating variance-covariance parameters and achieved better model convergence, confirming the hypothesis that high-dose iodine salt significantly lowers diastolic blood pressure (DBP).
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Background: Livestock-dependent communities in Africa's drylands disproportionately experience acute malnutrition, especially during drought seasons. We detail the design and implementation of the Livestock for Health (L4H) study aimed at determining the effect of providing livestock feed and nutritional counselling to prevent seasonal spikes of acute malnutrition.

Methods: The L4H study employed a 3-arm cluster randomized controlled trial to compare households in pastoralist settings in northern Kenya receiving livestock feeds during critical dry periods, with or without nutritional counseling, with control households.

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Diabetes is a major cause of morbidity and mortality worldwide yet preventable. Complications of undetected and untreated diabetes result in serious human suffering and disability. It negatively impacts on individual's social economic status threatening economic prosperity.

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Background: Nutrition-sensitive livestock interventions have the potential to improve the nutrition of communities that are dependent on livestock for their livelihoods by increasing the availability and access to animal-source foods. These interventions can also boost household income, improving purchasing power for other foods, as well as enhance determinants of health. However, there is a lack of synthesized empirical evidence of the impact and effect of livestock interventions on diets and human nutritional status in Africa.

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Background: The onset of COVID-19 and related policy responses made it difficult to study interactive health informatics solutions in clinical study settings. Instrumented log and event data from interactive systems capture temporal details that can be used to generate insights about care continuity during ongoing pandemics.

Objective: To investigate user interactions with a digital health wallet (DHW) system for addressing care continuity challenges in chronic disease management in the context of an ongoing pandemic.

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Background: Brucellosis is associated with massive livestock production losses and human morbidity worldwide. Efforts to control brucellosis among pastoralist communities are limited by scarce data on the prevalence and risk factors for exposure despite the high human-animal interactions in these communities. This study simultaneously assessed the seroprevalence of brucellosis and associated factors of exposure among pastoralists and their livestock in same households.

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Background: Kenya is faced with a triple burden of malnutrition which is multi-faceted with health and socio-economic implications. Huge geographical disparities exist, especially, in the arid and semi-arid lands exacerbated by inadequate resource allocation to the nutrition sector and challenges in multi-sectoral coordination and nutrition governance. UNICEF's Maternal and Child Nutrition Programme is a four-year (2018-2022) resilience-building, multi-sectoral program focused on pregnant and lactating women, mothers of children under five years and children under five years.

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Background: can be transmitted to humans primarily through inhaling contaminated droplets released from infected animals or consumption of contaminated dairy products. Despite its zoonotic nature and the close association pastoralist communities have with their livestock, studies reporting simultaneous assessment of exposure and risk-factors among people and their livestock are scarce.

Objective: This study therefore estimated the seroprevalence of Q-fever and associated risk factors of exposure in people and their livestock.

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The challenge of undernutrition (stunting and wasting) still remains a major health concern in children below 5 years of age in Africa, with the continent accounting for more than one third of all stunted children and more than one quarter of all wasted children globally. Despite the growing evidence on the role of agriculture interventions in improving nutrition, empirical evidence on the impact of livestock intervention on nutrition in Africa is scant. This review is aimed at determining whether livestock interventions are effective in reducing undernutrition in children below five years of age and in pregnant and lactating women in Africa.

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Diet is one of the modifiable lifestyle factors in management of kidney disease. We explored perceptions on adherence to dietary prescriptions for adults with chronic kidney disease on hemodialysis. This was a qualitative descriptive study.

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Objective: To estimate the direct and indirect costs of diabetes mellitus care at five public health facilities in Kenya.

Methods: We conducted a cross-sectional study in two counties where diabetes patients aged 18 years and above were interviewed. Data on care-seeking costs were obtained from 163 patients seeking diabetes care at five public facilities using the cost-of-illness approach.

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Article Synopsis
  • - The study examined the effectiveness of unattended automated office blood pressure (uAOBP) in screening for hypertension among a sample of 982 Kenyan adults, using 24-hour ambulatory blood pressure monitoring as a benchmark.
  • - Results indicated that while the average systolic BP readings from uAOBP were similar to those from 24-hour monitoring, there was wide variability and a notable drop in sensitivity as the blood pressure cutoffs increased from ≥130/80 mmHg to ≥140/90 mmHg.
  • - It was found that uAOBP was more accurate in detecting hypertension in overweight and obese individuals, highlighting the need for improved screening methods, as significant misclassification occurred in the general population.
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Introduction: Adherence to dietary prescriptions among patients with chronic kidney disease is known to prevent deterioration of kidney functions and slow down the risk for morbidity and mortality. This study determined factors associated with adherence to dietary prescription among adult patients with chronic kidney disease on hemodialysis.

Methods: A mixed-methods study, using parallel mixed design, was conducted at the renal clinics and dialysis units at the national teaching and referral hospitals in Kenya from September 2018 to January 2019.

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Background: Hypertension in low- and middle-income countries, including Kenya, is of economic importance due to its increasing prevalence and its potential to present an economic burden to households. In this study, we examined the patient costs associated with obtaining care for hypertension in public health care facilities in Kenya.

Methods: We conducted a cross-sectional study among adult respondents above 18 years of age, with at least 6 months of treatment in two counties.

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Progress of national Universal Salt Iodization (USI) strategies is typically assessed by household coverage of adequately iodized salt and median urinary iodine concentration (UIC) in spot urine collections. However, household coverage does not inform on the iodized salt used in preparation of processed foods outside homes, nor does the total UIC reflect the portion of population iodine intake attributable to the USI strategy. This study used data from three population-representative surveys of women of reproductive age (WRA) in Kenya, Senegal and India to develop and illustrate a new approach to apportion the population UIC levels by the principal dietary sources of iodine intake, namely native iodine, iodine in processed food salt and iodine in household salt.

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Cancer is the third leading cause of death in Kenya. However, there is scarce information on the nutritional status of cancer patients to guide in decision making. The present study sought to assess the risk of malnutrition, and factors associated with malnutrition and cachexia, among cancer out-patients, with the aim of informing nutrition programmes for cancer management in Kenya and beyond.

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Background: Malnutrition is a universal problem in cancer patients renowned as an important factor for increased morbidity, decreased quality of life and high mortality. Early diagnosis of malnutrition risk through nutrition screening followed by comprehensive and timely interventions reduces mortality associated with malnutrition. The Scored Patient-Generated Subjective Global Assessment (PGSGA) method has been proved efficient in identifying cancer patients with nutrition challenges and guiding appropriate interventions.

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Background. Inflammation, together with related oxidative stress, is linked with the etiology of kwashiorkor, a form of severe acute malnutrition in children. A diet rich in anti-inflammatory and antioxidant phytochemicals may offer potential for the prevention and treatment of kwashiorkor.

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  • Machakos and Makueni counties in Kenya face challenges related to land degradation, climate change, and food insecurity, impacting both women and children's dietary health.
  • A study involving 277 woman-child pairs found no significant differences in food security or dietary diversity between lower midland agroecological zones LM4 and LM5.
  • The research highlighted that severe food insecurity is linked to poor nutritional status in children, particularly older ones, indicating that a simple dietary diversity score could underestimate food insecurity in semi-arid regions.
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  • Key risk factors for metabolic syndrome identified include raised blood pressure, increased waist circumference, and low HDL cholesterol, while issues like raised fasting glucose and triacylglycerides appear less frequently.
  • The research highlights the need for greater awareness and preventive strategies from the Kenyan government, along with longitudinal studies to better understand the causes of metabolic syndrome in the country.
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