Sphenoidal pneumosinus dilatans associated compressive optic neuropathy: A case series of four adolescent patients.

Visual impairment caused by pneumosinus dilatans (PSD) among adolescents is a rare condition, which is associated with a high blinding rate due to the lack of clinical manifestations and effective treatment. The use of magnetic resonance imaging (MRI) and computed tomography (CT) may be helpful in diagnosis of PSD, and the endoscopic transnasal optic nerve decompression (ETOND) can improve the vision of PSD patients with visual impairments. This case series report detailing the diagnosis and treatment of visual impairments caused by PSD has improved clinicians' understanding of this disease and helped reduce misdiagnoses and missed diagnoses.

MX1 and UBE2L6 are potential metaflammation gene targets in both diabetes and atherosclerosis.

Background: The coexistence of diabetes mellitus (DM) and atherosclerosis (AS) is widespread, although the explicit metabolism and metabolism-associated molecular patterns (MAMPs) responsible for the correlation are still unclear.

Methods: Twenty-four genetically wild-type male Ba-Ma mini pigs were randomly divided into five groups distinguished by different combinations of 90 mg/kg streptozotocin (STZ) intravenous injection and high-cholesterol/lipid (HC) or high-lipid (HL) diet feeding for 9 months in total. Pigs in the STZ+HC and STZ+HL groups were injected with STZ first and then fed the HC or HL diet for 9 months.

Correlation of preoperative seizures with a wide range of tumor molecular markers in gliomas: An analysis of 442 glioma patients from China.

Purpose: Epileptic seizures often develop in 40-70 % of glioma patients and have a significant impact on patients' quality of life. Many biomarkers have been suggested to be associated with glioma-related preoperative seizures (GPS). The purpose of the present study was to investigate the possible correlation between GPS and clinicopathological factors and a wide range of glioma-associated molecular markers (GMMs).