Publications by authors named "Bugra Kaya"

We wanted to present a rare case of metastatic grade 2 spinal ependymoma with an atypical course at the time of diagnosis. Temozolomide plus capecitabine chemotherapy was started in May 2018 on a 30-year-old female patient with sacral ependymoma who had extensive lung metastases at the time of diagnosis. The patient remained in remission for approximately 29 months, and the current chemotherapy was continued until it progressed in November 2020.

View Article and Find Full Text PDF

Objectives: Brain imaging of regional metabolic changes in cancer patients can provide insights into cancer biology. We aimed to detect regional metabolic changes in the brains of untreated lung cancer patients without brain metastases using 2-deoxy-2-[18F]fluoroglucose PET/computed tomography.

Methods: The study included 44 lung cancer patients and 17 non-cancer patients as controls.

View Article and Find Full Text PDF

Stercoral colitis is a colonic inflammation caused by fecal impaction. It is now more commonly discussed in the literature due to its clinical significance, which has gained recognition in recent years. Delayed diagnosis may result in complications such as sepsis and perforation, which have a high mortality rate.

View Article and Find Full Text PDF

Background: Studies on single nucleotide polymorphisms (SNPs) in non-small cell lung cancer (NSCLC) suggest that DNA repair capacity may have prognostic implications for disease recurrence and survival. However, there is no study investigating the relationship between SNPs and the risk of metastasis at the time of initial diagnosis in patients with NSCLC.

Objective: This study aimed to investigate the potential predictive value of SNPs in detecting the risk of metastasis at the time of initial diagnosis and poor prognosis in patients with NSCLC.

View Article and Find Full Text PDF

Extramedullary plasmacytoma (EMP) occurs as a result of abnormal proliferation of plasma cells outside the bone marrow. Breast plasmacytomas are rare. Radiologically, they can be confused with benign and malignant lesions of the breast.

View Article and Find Full Text PDF

Pulmonary alveolar microlithiasis is a rare disease characterized by accumulating intraalveolar small calcium phosphate stones. The disease is slow and does not show any signs in the early stages, but the shortness of breath, cough, and right heart failure may develop as it progresses. Methylene diphosphonate used in bone scintigraphy shows high uptake of calcium deposits in the alveoli and causes diffuse increased radiopharmaceutical uptake in the lungs.

View Article and Find Full Text PDF

Purpose: In this study, we aimed to evaluate the prognostic significance of adipose tissue distribution and metabolic activity in PET/CT to predict survival in patients with metastatic colorectal cancer (mCRC).

Methods: The volume, density (HU), and FDG uptake (standardized uptake value (SUV)) of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) and maximum FDG uptake of the tumor tissue were measured. Subcutaneous adipose tissue of volume-to-density ratio (SAT ratio) was calculated.

View Article and Find Full Text PDF

We present the 68Ga-PSMA and 18F-FDG PET/CT findings comparatively of a 67-year-old prostate cancer and malignant melanoma patient who had COVID-19 pneumonia 3 months ago. In 68Ga-PSMA PET/CT, ground-glass opacities showing markedly increased PSMA uptake were observed in the patient's lungs. It was learned that the patient had COVID-19 pneumonia 3 months ago and was treated in the intensive care unit for 13 days.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to determine how well volumetric PET parameters like metabolic tumor volume (MTV) and total lesion glycolysis (TLG) help predict prostate carcinoma in patients with prostate incidentalomas (PIs) identified through 18F-FDG PET/CT scans.
  • It involved a retrospective analysis of 107 patients where malignant PIs showed significantly higher SUVmax, MTV, and TLG values compared to benign cases, with volumetric parameters outperforming SUVmax in predictive capability.
  • The findings indicate that MTV and TLG may provide essential clinical information for diagnosing malignancy in PIs, with TLG 2.5 achieving high sensitivity (94.1%) and specificity (82.6%) for malignancy prediction.
View Article and Find Full Text PDF
Article Synopsis
  • The study examines the prognostic significance of the maximum standardized uptake value (SUV) from PET/CT scans in early-stage nonsmall cell lung cancer (NSCLC) patients who underwent surgery.
  • The research included 92 patients, analyzing their preoperative PET/CT results to compare disease-free survival (DFS) rates based on whether their SUV values were above or below a cutoff of 13.6.
  • Results showed that higher SUV values were associated with shorter DFS in Stage I and II NSCLC patients, indicating that SUV is a valuable prognostic indicator for survival outcomes.
View Article and Find Full Text PDF

Intravascular large B-cell lymphoma is a rare type of non-Hodgkin lymphoma characterized by intravascular proliferation of clonal lymphocytes within the lumen of small vessels, which is often fatal. Diffuse FDG uptake in the lung without clear/evident CT findings, "hot lung," is quasi-pathognomonic for lung intravascular large B-cell lymphoma. In this report, we present the case of a 43-year-old man who was diagnosed as having intravascular lymphoma thanks to this rare finding.

View Article and Find Full Text PDF

Objectives: The objective of this study was to compare the results of transthoracic biopsies performed through the use of FDG PET/CT imaging with the results of transthoracic needle biopsy performed without using the FDG PET/CT imaging.

Methods: The medical files of a total of 58 patients with pulmonary and mediastinal masses. A total of 20 patients, who were suspected of malignancy with the SUVmax value of over 2.

View Article and Find Full Text PDF

Background: Osteoporosis is a widespread metabolic bone disease representing a global public health problem currently affecting more than two hundred million people worldwide. The World Health Organization states that dual-energy X-ray absorptiometry (DXA) is the best densitometric technique for assessing bone mineral density (BMD). DXA provides an accurate diagnosis of osteoporosis, a good estimation of fracture risk, and is a useful tool for monitoring patients undergoing treatment.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to explore how chemotherapy affects (18)F-FDG uptake in the liver and mediastinal blood pool (MBP) in patients with non-Hodgkin's lymphoma.
  • - Twenty-three patients underwent PET/CT scans at different stages (baseline, interim, and post-chemotherapy) to compare SUVmax and SUVmean values.
  • - Results showed no significant changes in (18)F-FDG uptake in the liver and MBP after chemotherapy, indicating that R-CHOP treatment does not impact these areas significantly.
View Article and Find Full Text PDF

The differential diagnosis at the inguinal region is very important for hypermetabolic foci because of the possibility of metastasis at this level in cancer patients ongoing PET imaging for detection of metastases. It is important to distinguish this activity from other possible malignant and benign conditions such as lymph node activity, testicular cancer, metastatic disease activity, inflammation and urine skin contamination artefact. A 66-year-old male patient with operated colon cancer and liver metastasis was referred for PET/CT examination for re-staging because of suspicious metastases.

View Article and Find Full Text PDF

Primitive neuroectodermal tumor (PNET) of the chest wall or Askin's tumor is a rare neoplasm of chest wall. It most often affects children and adolescents and is a very rare tumor in adults. In this case report, we present an Askin's tumor occurred in a 73-year-old male.

View Article and Find Full Text PDF

Objective: To compare the effects of surgical (ie, earlier) and natural (ie, later) menopause on climacteric symptoms, osteoporosis, and metabolic syndrome.

Method: The study was conducted with 94 women who underwent hysterectomy and bilateral oophorectomy and 95 women who were older than 40 years and in natural menopause. None had received hormone therapy or osteoporosis treatment.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionm0hnqqoibchf50gjl7rbql7risb1noif): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once