[Malignant melanoma of the urinary bladder].

Primary malignant melanoma of the genitourinary tract is a rare lesion. We report the case of a 52-year-old man with primary manifestation of metastatic melanoma in the bladder. Multimodal therapy with transurethral tumor resection and systemic interferon/dacarbazine was not successful and the patient died 18 months later.

Prostatic sarcoma of the Ewing family in a 33-year-old male - A case report and review of the literature.

Ewing sarcoma is the second most common primary bone tumor seen in children and adolescents, typically presenting between 10 and 20 years of age. Extraosseous sarcomas of the Ewing family in adults are rare. We report a manifestation of this tumor entity in the periprostatic tissue of a 33-year-old male and discuss our treatment approach.

Accuracy of cardiovascular magnetic resonance in myocarditis: comparison of MR and histological findings in an animal model.

Background: Because endomyocardial biopsy has low sensitivity of about 20%, it can be performed near to myocardium that presented as late gadolinium enhancement (LGE) in cardiovascular magnetic resonance (CMR). However the important issue of comparing topography of CMR and histological findings has not yet been investigated. Thus the current study was performed using an animal model of myocarditis.

[Primary syphilitic lesion mimicking penile cancer. Atypical manifestation with an unconventional diagnostic approach].

Syphilis is the great imitator in medicine. Correct diagnosis of this disease can be quite difficult nowadays, after years of rare occurrence but current increasing incidence. Atypical manifestations of syphilis are often misinterpreted and lead to incorrect diagnosis and inappropriate therapy.

Top-hat shaped corneal trephination for penetrating keratoplasty using the femtosecond laser: a histomorphological study.

Purpose: To evaluate a novel technique for penetrating keratoplasty (PK) with the use of a new software algorithm for the femtosecond laser, designed to create penetrating cuts in a top hat configuration.

Design: Consecutive histomorphological case series.

Patients And Methods: Twelve eyes of 12 patients underwent penetrating keratoplasty by means of a 60-kHz femtosecond laser (IntraLase, Irvine, California) with a software specifically developed for corneal surgery.

Acute myocarditis in a rat model: late gadolinium enhancement with histopathological correlation.

The aim of the current study was to use an established animal model of autoimmune myocarditis and to judge the ability of cardiovascular MRI (CMR) in quantitatively measuring the extent of myocardial involvement compared with histopathological measurement of severity and extent. Experimental autoimmune myocarditis (EAM) was induced in 10 male Lewis rats. On day 21, all animals were investigated by CMR to measure the extent of late gadolinium enhancement (LGE).

[Hepatic angiomyolipoma--a rare liver tumor].

A 22-year-old woman was treated for a hepatic lesion with a high suspicion of a liver adenoma at another hospital. The patient presented with unspecific abdominal pain. Further physical examination was unremarkable.

Corneal femtosecond laser keratotomy results in isolated stromal injury and favorable wound-healing response.

Purpose: To examine the corneal repair response after intrastromal femtosecond (fs) laser keratotomy.

Methods: Twelve rabbits underwent monocular intrastromal keratotomy performed with an fs laser at a preoperatively determined corneal depth of 160 to 200 microm. The fs laser-induced corneal repair response was compared with that of nonoperated control eyes and eyes treated with photorefractive keratectomy (PRK).

[Cerebral lymphomatoid granulomatosis. A case report].

We present the case of a 57-year-old patient who was admitted with fever and disorientation. The cerebrospinal fluid showed a mild pleocytosis and increased protein content. MR imaging revealed multiple lesions, particularly in the subcortical white matter, with spot like central contrast enhancement.

Corneal trephination with the femtosecond laser.

Purpose: To evaluate the feasibility and cut quality of corneal trephination in human donor corneal tissue with the femtosecond laser.

Methods: Twelve human corneoscleral discs were inserted in an artificial anterior chamber. After corneal thickness measurement and tonometry, the cornea was mounted on a femtosecond laser (FEMTEC; 20/10 Perfect Vision, Heidelberg, Germany) through a contact lens (patient interface).

Correlation between clinical in vivo confocal microscopic and ex vivo histopathologic findings of Salzmann nodular degeneration.

Purpose: To report clinical, in vivo confocal microscopy and ex vivo histopathologic findings of Salzmann nodular degeneration (SND).

Methods: A 48-year-old woman with symptoms of ocular irritation and decreased visual acuity caused by SND in both eyes was treated by corneal scraping and phototherapeutic keratectomy (PTK). Slit-lamp biomicroscopy, in vivo confocal microscopy, ex vivo light microscopy, immunohistology, and corneal topography were performed.

Liver transplantation in a 29-year-old patient with gallbladder carcinoma complicating primary sclerosing cholangitis.

Patients with primary sclerosing cholangitis (PSC) are at increased risk for cholangiocarcinoma. This tumor usually is a fatal complication, median survival after diagnosis is less than six months. In an asymptomatic 29-year-old patient with long-standing PSC and ulcerative colitis, routine abdominal ultrasound demonstrated an irregular mass, 11 x 13 mm, in the gallbladder.

[Calcified inclusions in a popliteal cyst as a rare cause of persistent knee pain and recurrent effusions].

Popliteal cysts may occur with diseases of the knee and may cause several complications. We report about a patient with a popliteal cyst, that contained calcified concrements after a femur fracture and a complex knee injury and that we found to be a rare cause of persisting knee pain and effusions. The etiology of the concrements will be discussed, that we think are more likely to be posttraumatic loose joint bodies than traumatically induced chondromatosis.

[Systemic fungal infections in hematologic neoplasms. An autopsy study of 1,053 patients].

Background: Mycoses are common complications of haematological neoplasias. For successful antimycotic treatment, a knowledge of preferential underlying disease, frequency, species and site of the mycosis is of importance.

Patients And Methods: Postmortem material comprising clinical data, autopsy protocols and histological sections obtained between 1976 and 1990 from 1,053 patients with leukaemia and malignant lymphomas following antineoplastic therapy was analysed retrospectively.

[Cancers in medial neck cysts--3 case reports].

1% of thyroglossal duct cysts are supposed to develop carcinoma. In most cases papillary carcinoma is found deriving from ectopic thyroid tissue. As far as squamous cell carcinomas are concerned, worldwide only eleven cases have been reported so far.