Radioprotective Effects of Zinc and Selenium on Mice Spermatogenesis.

Background: Spermatogenesis system is one of the most radiosensitive organs in the body. A usual therapeutic dose of radiation such as the conventional 2 Gy in each fraction of radiotherapy and lower doses seen in diagnostic radiology or a radiation disaster affect the process of spermatogenesis potently. Selenium and zinc are two important elements playing key roles in the development of sperms and also have radioprotective effects.

LESS THAN HALF OF ACL-RECONSTRUCTED ATHLETES ARE CLEARED FOR RETURN TO PLAY BASED ON PRACTICE GUIDELINE CRITERIA: RESULTS FROM A PROSPECTIVE COHORT STUDY.

Background: A recently published Dutch practice guideline emphasizes criterion-based rehabilitation after anterior cruciate ligament reconstruction (ACLR) instead of time-based. As a consequence of this criterion-based rehabilitation, return to play is only suggested when athletes meet specific return to play (RTP) criteria.

Purpose: The goal of this prospective observational study was to analyze if physical therapists adhere to ACLR practice guideline RTP criteria for testing and return to sport decisions, and to explore whether there is a difference in adherence between physical therapists specialized in sports versus those who are not.

Cervical lymph node metastasis in squamous cell carcinoma of the buccal mucosa: a retrospective study on pattern of involvement and clinical analysis.

Background: The study was performed with an aim to map the pattern of metastasis of squamous cell carcinomas of buccal mucosa to various cervical lymph node levels and analyze its correlation with primary tumor size and histo-pathological grading.

Material And Methods: 254 patients with squamous cell carcinoma of the buccal mucosa treated with surgery first approach were analyzed retrospectively. The tumor size was noted from pre-operative CT Scans and were divided into early and advanced tumors.

Designing complex radial heterostructures of Te/BiTe and Te/Bi Pb Te nanowires: fundamental mechanistic insights into nanowire growth and evolution.

Metal telluride/Te heterostructure nanowires are important thermoelectric materials and it is important to be able to tune these materials according to the requirement of the application. In order to do so, a good understanding of the reaction mechanism and critical observation of the evolution of the nanowire heterostructure during the course of reaction is essential. Here, single crystalline, anisotropic Te core/BiTe shell nanowires have been synthesized by a facile template-based wet chemical synthesis method.

Severe type 2 leprosy reaction with COVID-19 with a favourable outcome despite continued use of corticosteroids and methotrexate and a hypothesis on the possible immunological consequences.

Type 2 leprosy reaction (T2LR), or Erythema Nodosum Leprosum (ENL), often poses a therapeutic challenge to clinicians and commonly requires long courses of steroids for control. While immunosuppressants are known to achieve control and lower steroid dependence in T2LR, the prospect of managing a severe T2LR in conjunction with COVID-19, with the concern of worsening COVID-19 with long-term immunosuppression has not previously been encountered. We report a case of severe T2LR treated with oral steroids and methotrexate, with COVID-19 infection acquired during hospital stay, and a favourable outcome achieved despite the continued use of immunosuppressants.

In Vitro bioactivity, biocompatibility and corrosion resistance of multi-ionic (Ce/Si) co-doped hydroxyapatite porous coating on Ti-6Al-4 V for bone regeneration applications.

Dual-doped hydroxyapatite (Ce/Si doped HAP) coating with admirable bacterial resistance and enriched bioactivity was fabricated via spin-coating technique. In this study, Ce/Si co-doped hydroxyapatite was coated on Ti-6Al-4 V substrates as a triple layer with extreme centrifugal force (2000 RPM, 3000 RPM and 4000 RPM) to improve the biological performance of the coating in terms of enhanced bone apposition. Further, the coated substrate was characterized by XRD, FTIR and SEM-EDS techniques.

Synthesis, characterization, molecular docking and anticancer studies of fluoroaniline derivatives of hydroxybenzoquinone and hydroxynaphthoquinone.

Two series of fluoro substituted-anilino derivatives of naturally occurring hydroxybenzoquinone and hydroxynaphthoquinone were synthesized using TFA as catalyst to improve the product yield. Recently, fluorine containing compounds are being used as anticancer drugs. The aim of this study is to find compounds that are active against melanoma cells.

Cardiometabolic vigilance in COVID-19 and resource husbandry in resource-challenged times: Clinical practice- based expert opinion.

Background And Aims: The ongoing pandemic of coronavirus disease 2019 (COVID-19) is rapidly evolving, thereby posing a profound challenge to the global healthcare system. Cardiometabolic disorders are associated with poor clinical outcomes in persons with COVID-19. Healthcare challenges during the COVID-19 pandemic are linked to resource constraints including shortage of Personal Protective Equipment's (PPE), laboratory tests and medication.

Optimization of extraction parameters and stabilization of anthocyanin from onion peel.

A large amount of onion waste is produced by the food industries. This onion waste contains high-value functional ingredients, since several compounds and nutrients are present in onion peel. The objective of this work is to extract and stabilize the anthocyanin from onion peel waste in various forms.

Assessment of polyunsaturated fatty acids: A self-report and biomarker assessment with a racially and ethnically diverse sample of women.

Polyunsaturated fatty acids (PUFAs) play an important role in human health, influencing chronic disease and mortality. Food Frequency Questionnaires (FFQs) are widely used to assess self-reported diet, but they can be subject to a variety of errors. Accordingly, an accurate assessment of diet is crucial in nutrition research.

Sperm chromatin structure assay versus sperm chromatin dispersion kits: Technical repeatability and choice of assisted reproductive technology procedure.

Objective: The sperm DNA fragmentation index (DFI) guides the clinician's choice of an appropriate assisted reproductive technology (ART) procedure. The DFI can be determined using commercially available methodologies, including sperm chromatin dispersion (SCD) kits and sperm chromatin structure assay (SCSA). Currently, when DFI is evaluated using SCD kits, the result is analyzed in reference to the SCSA-derived threshold for the choice of an ART procedure.

Evaluation of telomere length and genotoxicity among asphalt associated workers.

There are contradictory reports about bitumen exposure and malignancy risk worldwide. Also, the evidence for genotoxicity risk among workers occupationally exposed to asphalt is insufficient. The study intended to evaluate particulate matter 10 (PM) at the workplace and biomarkers of genotoxicity effects among a group of asphalt workers in and around Bangalore, India.

Patient and Public Involvement in Sexual and Reproductive Health: Time to Properly Integrate Citizen's Input into Science.

Evidence-based sexual and reproductive health is a global endeavor without borders. Inter-sectorial collaboration is essential for identifying and addressing gaps in evidence. Health research funders and regulators are promoting patient and public involvement in research, but there is a lack of quality tools for involving patients.

Effect of Neodymium Doping on MRI Relaxivity of Gadolinium Oxide Nanoparticles.

Background: Gadolinium oxide nanoparticles as positive contrast material of magnetic resonance imaging (MRI) have attracted a great attention due to the appropriate magnetic properties. One of the most desirable features of these nanoparticles is their ability of doping with other lanthanides which can change their properties.

Objective: This study aimed to investigate the effect of neodymium doping on MRI relaxivity of the gadolinium oxide nanoparticles.

Prevalence and Impact of Atrial Fibrillation in a Cohort of Patients with Hypertrophic Cardiomyopathy in Ireland.

Aims: Atrial fibrillation (AF) is the most common sustained arrhythmia in patients with hypertrophic cardiomyopathy (HCM), and is associated with deterioration in clinical status and outcome. To date, no data have been published pertaining to AF in an Irish HCM population.

Methods And Results: 159 patients with HCM attending St Vincent's University Hospital and Blackrock Clinic, Dublin, were identified.

Recommendations, Practices and Infrastructural Model for the Dental Radiology Set-up in Clinical and Academic Institutions in the COVID-19 Era.

The pandemic of Coronavirus disease (COVID-19) has emerged as a global catastrophe that is plaguing mankind. In the past eight months since the world discovered about COVID-19, we learned a lot about server acute respiratory syndrome coronavirus 2 (SARS CoV-2) and perhaps there is much more to discover and understand about the virus. With the current understanding of the disease, we assume it will remain in an active state of transmission and progression among the community for a long time.

High-flow oxygen and pro-serotonin agents for non-interventional treatment of post-dural-puncture headache.

Objective: Post dural puncture headache (PDPH) is a common complication in patients following diagnostic or therapeutic lumbar puncture, procedures requiring epidural access, and spinal surgery. Epidural blood patch (EBP), the gold standard for the treatment of this pathology requires training not provided to emergency physicians. In addition, the presence of concomitant pathology and abnormal laboratory values are contraindications to perform EBP.

Transfer Learning Based Automatic Human Identification using Dental Traits- An Aid to Forensic Odontology.

Forensic Odontology deals with identifying humans based on their dental traits because of their robust nature. Classical methods of human identification require more manual effort and are difficult to use for large number of Images. A Novel way of automating the process of human identification by using deep learning approaches is proposed in this paper.

Hot liver on 18F-FDG PET/CT imaging-a quandary for oncoradiologists in South Asia.

A 56-year-old female presented with intermittent hemoptysis and was diagnosed with lung cancer. F-fluorodeoxyglucose positron emission tomography/CT for staging revealed hypermetabolic liver (hot liver), uptake in the mediastinal lymph nodes and reduced uptake in the kidneys. Unexpectedly, liver biopsy findings were consistent with tuberculous infection.

Comparative Analysis of Safety and Efficacy of Topography-Guided Customized Cross-linking and Standard Cross-linking in the Treatment of Progressive Keratoconus.

Purpose: To compare the safety and efficacy of topography-guided customized corneal cross-linking (PiXL) with standard cross-linking (CXL) for the treatment of progressive keratoconus.

Methods: In a prospective interventional analysis, the eyes of patients with progressive keratoconus underwent standard cross-linking (homogenous 9-mm ultraviolet-A irradiation of 9 mW/cm2 delivering a total fluence of 5.4J/cm2) versus topography-guided customized cross-linking (30 mW/cm2 pulsed irradiance with a total fluence ranging from 5.

Automatic classification methods for detecting drowsiness using wavelet packet transform extracted time-domain features from single-channel EEG signal.

Background: Detecting human drowsiness during some critical works like vehicle driving, crane operating, mining blasting, etc. is one of the safeguards to prevent accidents. Among several drowsiness detection (DD) methods, a combination of neuroscience and computer science knowledge has a better ability to differentiate awake and sleep states.

Syndrome of inappropriate antidiuretic hormone release as the initial presentation of adenocarcinoma of the colon.

Syndrome of inappropriate antidiuretic hormone release (SIADH) is a condition defined by the unsuppressed release of antidiuretic hormone (ADH) from the pituitary gland or nonpituitary sources or its continued action on vasopressin receptors. Of the many causes of SIADH, an important one includes tumours that secrete ADH. We describe a rare case of a patient with colonic adenocarcinoma presenting initially as SIADH.

Mass transfer dynamics of simultaneous water gain and solid loss during soaking of pigeon pea grains.

Pigeon pea is the most prominently used protein source for human consumption. This is one of the leading pulse utilized in various applications in food processing. Soaking is one of the mandatory unit operation required to convert it from raw to a consumable form.

Participatory Workshop-Based Intervention for Better Preparedness and Awareness About Disaster Management Among Accredited Social Health Activists in India: A Brief Report.

Objectives: The aim of this study was to evaluate the effectiveness of training programs in improving the knowledge about disaster management among Accredited Social Health Activists (ASHAs) in Mysuru, India.

Methods: A quasi-experimental study was conducted among 40 ASHAs of 3 Primary Health Centers in Mysuru district. A 3-h disaster management training and workshop followed by a mock-drill was organized in each center.