Publications by authors named "Buesranur Seker"

Molybdate, an oxidized form of molybdenum, facilitates molybdenum to be taken into cell, and thus to be included as a cofactor in the structure of enzymes necessary to ensure homeostasis. Although this compound provides the catalysis and electron transport of many biochemical reactions, it causes serious health problems in animals at high concentrations. For this reason, its recovery of water resources is one of the main subjects of scientific studies called bioremediaiton.

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Blood-derived biomaterials with high platelet content have recently emerged as attractive products for tissue engineering and regenerative medicine (TERM). Platelet-derived bioactive molecules have been shown to play a role in wound healing and tissue regeneration processes by promoting collagen synthesis, angiogenesis, cell proliferation, migration, and differentiation. Given their regenerative potential, platelet-rich blood derivatives have become a promising treatment option for use in a variety of conditions.

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Objective: We aimed to elucidate the histopathological pre-diagnosis of cranial gliomas with magnetic resonance imaging (MRI) techniques in gliomas.

Method: A total of 82 glioma patients were enrolled to our study. Pre-operative conventional MRI images (non-contrast T1/T2/flair/contrast-enhanced T1) and advanced MRI images (DAG and ADC mapping, MRI spectroscopy and perfusion MRI [PMRI]) were analyzed.

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Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in asthma management remain limited. This registry-based study evaluated the use of montelukast in adult asthma patients, examining demographic and disease characteristics, asthma control status, asthma phenotypes, presence of atopy, and treatment regimens. Among 2053 patients analyzed, 61.

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Introduction: Clinicians are the conduits of high-quality care delivery. Clinicians have driven advancements in pharmacotherapeutics, devices, and related interventions and improved morbidity and mortality in patients with congestive heart failure over the past decade. Yet, the management of congestive heart failure has become extraordinarily complex and has fueled recommendations from the American Heart Association and the American College of Cardiology to optimize the composition of the care team to reduce the health, economic, and the health system burden of high lengths of stay and hospital charges.

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This study explores the integration of nanotechnology and Long Short-Term Memory (LSTM) machine learning algorithms to enhance the understanding and optimization of fuel spray dynamics in compression ignition (CI) engines with varying bowl geometries. The incorporation of nanotechnology, through the addition of nanoparticles to conventional fuels, improves fuel atomization, combustion efficiency, and emission control. Simultaneously, LSTM models are employed to analyze and predict the complex spray behavior under diverse operational and geometric conditions.

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Introduction: Alzheimer's disease is a chronic brain disease that includes memory and language disorders. This disease, which is considered the most common cause of dementia worldwide, accounts for 60-80% of all dementia cases. Recent studies suggest that the cerebellum may play a role in cognitive functions as well as motor functions.

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Introduction: It is known that combat athletes frequently lose weight before a competition. This study aimed to determine the weight loss methods before an official championship and the effects of these weight loss methods on the performance of wrestlers.

Method: The sample of the study consisted of 350 competitive wrestlers.

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For several years, our society has been experiencing an aging of the population. Concurrently, there has been an observable increase in the population of nursing homes (EHPAD). The context of a global epidemic and the public health measures implemented to address it have underscored the vulnerability of our elderly population and the need for remote consultations to ensure continuity of care.

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Current guidelines recommend adding long-acting muscarinic antagonists (LAMAs) in patients with uncontrolled asthma, despite the use of moderate to high doses of inhaled steroid-long-acting beta agonists (ICS/LABA). This study aims to analyze the factors related to the prescription of add-on LAMA in clinical practice for asthma patients, shedding light on physicians' preferences. This study included adult asthma patients on add-on LAMA and ICS/LABA monitored for at least one year in a national registry comprising 2053 asthmatics.

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Objective: In the current study, we aimed to ascertain the levels of heavy metals and radioactive elements in the ovarian follicular fluids of pregnant and non-pregnant Kyrgyz mares.

Materials And Methods: To this end, follicular fluids were obtained from 49 Kyrgyz mares aged 3-5 years. The mares were in various stages of pregnancy (Group 1, 27) or were non-pregnant (Group 2, 22).

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Objectives: This study sought to assess the diagnostic value of ultrasonography (USG) and cone-beam computed tomography (CBCT) for the visibility of periodontal defects.

Materials And Methods: We created 37 periodontal defects (dehiscence and fenestration) in fresh sheep mandibles. Two dentomaxillofacial radiologists assessed the CBCT and ultrasonographic images for the presence of defects.

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We aimed to investigate whether pulsed magnetic fields (PMFs) (1 mT) may have preventive effects on myocardial damage and apoptosis in rats with sepsis. Twenty-eight adult Wistar albino rats were evenly distributed among four experimental groups, each consisting of seven rats: SH, LF-PMF, HF-PMF, and CLP. Sepsis induction was carried out via the cecal ligation and puncture (CLP) method, while rats in the LF-PMF and HF-PMF groups were exposed to 7.

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Background And Aim: The purpose of this research was to ascertain how exposure to extremely low-frequency pulsed electromagnetic fields (ELF-PEMFs) at varying intensities affects apoptosis-related protein expression levels and liver morphology in rats.

Materials And Methods: In this experimental study, 40 Wistar albino rats were randomly divided into 4 groups, with 10 animals in each group: Control, Sham, 1 milli Tesla (1mT), and 5 mT groups. The control group did not expose any application during the experiment.

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Metal nanoparticles (NPs) are commonly used nanomaterials, however concerns have been raised about their toxicity. Although a few studies have reported the toxicity of NPs on cells, they have generally been restricted to a limited variety of NPs, inappropriate cell lines, or culture methods. Thus, the adverse effects remain inadequately understood, necessitating further analysis.

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Background: Microglia play a critical role in neurodegenerative disorders, such as Alzheimer's disease, where alterations in microglial function may result in pathogenic amyloid-β (Aβ) accumulation, chronic neuroinflammation, and deleterious effects on neuronal function. However, studying these complex factors in vivo, where numerous confounding processes exist, is challenging, and until recently, in vitro models have not allowed sustained culture of critical cell types in the same culture.

Objective: We employed a rat primary tri-culture (neurons, astrocytes, and microglia) model and compared it to co-culture (neurons and astrocytes) and mono-culture (microglia) to study microglial function (i.

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Background: The main purpose of the study is to comprehensively evaluate population-level survival disparities stage-by-stage, according to specific anatomical colon segments, and based on prognosis as defined by lymph nodes among patients who have undergone curative resection for non-metastatic colon cancer.

Methods: The study was conducted from the Surveillance Epidemiology and End Result (SEER) program from the USA. Patients who underwent surgery for colon adenocarcinoma between 2000 and 2019 were identified.

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RAG2 deficiency is characterized by a lack of B and T lymphocytes, causing severe lethal infections. Currently, RAG2 deficiency is treated with a Hematopoietic Stem Cell transplantation (HSCT). Most conditioning regimens used before HSCT consist of alkylating myelotoxic agents with or without irradiation and affect growth and development of pediatric patients.

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Article Synopsis
  • A new ferrocene-decorated cyclotriphosphazene compound was synthesized using the click method, confirming structures through various spectroscopic techniques.
  • The optical band gaps of the compounds were measured, showing values ranging from 3.46 eV to 4.75 eV, with the final product exhibiting favorable electronic properties based on the hopping conduction mechanism.
  • Diodes made from these compounds demonstrated excellent rectification behavior and photodiode properties under sunlight, suggesting potential applications in optoelectronic devices.
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Article Synopsis
  • - Testicular ischemia reperfusion (I/R) injury poses a major issue in urology, and the study investigates the protective effects of the antioxidant -Anethole on this condition in male rats.
  • - Twenty-eight rats were divided into four groups, with two groups receiving 100 or 200 mg/kg -Anethole during ischemia; results showed significant improvements in the I/R + 200 group compared to the I/R group, particularly in reducing oxidative stress and inflammation.
  • - The findings suggest that -Anethole may offer gonadoprotective benefits during testicular I/R injury, specifically by influencing the transcription factors STAT3 and NF-κB, but further evaluation of potential benefits and side effects
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Cancer therapy can be limited by potential side effects, and bacteria-based living cancer therapeutics have gained scientific interest in recent years. However, the full potential of bacteria as therapeutics has yet to be explored due to engineering challenges. In this study, we present a bacterial device designed to specifically target and eliminate breast cancer cells.

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Background: Tennis requires movement abilities in changing playing situations. This article investigates the relationship between lower extremity strength asymmetry ratio and linear and multidimensional running performances in female tennis players.

Methods: A total of 56 female tennis players, with a mean age of 15.

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The aim of the present study was to determine the views and thoughts of dog owners in Türkiye on animal welfare. The research material consisted of data obtained from face-to-face surveys with 172 randomly selected dog owners. Half of the dog owners (54,7 %) were aware of the concept of animal welfare, and almost two-thirds (61,6 %) organized their dogs' living spaces according to animal welfare principles.

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Introduction: This study aimed to evaluate the relationship between pathological and clinical risk classifications in newly diagnosed prostate cancer patients, and Ga-PSMA PET/CT data and serum Prostate Specific Antigen (PSA) values.

Method: A total of 203 patients who were diagnosed with prostate cancer between 2019 and 2023, who had not yet received treatment and who underwent Ga-PSMA PET/CT for staging purposes were included in this study.

Results: There was a substantial correlation between D'Amico risk classification, Gleason score, ISUP classification, and the presence or absence of metastasis ( < 0.

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