The association of workforce configurations with length of stay and charges in hospitalized patients with congestive heart failure.

Introduction: Clinicians are the conduits of high-quality care delivery. Clinicians have driven advancements in pharmacotherapeutics, devices, and related interventions and improved morbidity and mortality in patients with congestive heart failure over the past decade. Yet, the management of congestive heart failure has become extraordinarily complex and has fueled recommendations from the American Heart Association and the American College of Cardiology to optimize the composition of the care team to reduce the health, economic, and the health system burden of high lengths of stay and hospital charges.

Nanotechnology and LSTM machine learning algorithms in advanced fuel spray dynamics in CI engines with different bowl geometries.

This study explores the integration of nanotechnology and Long Short-Term Memory (LSTM) machine learning algorithms to enhance the understanding and optimization of fuel spray dynamics in compression ignition (CI) engines with varying bowl geometries. The incorporation of nanotechnology, through the addition of nanoparticles to conventional fuels, improves fuel atomization, combustion efficiency, and emission control. Simultaneously, LSTM models are employed to analyze and predict the complex spray behavior under diverse operational and geometric conditions.

Radio-Anatomical Assessment of Cerebellum Volume in Individuals with Alzheimer's Disease.

Introduction: Alzheimer's disease is a chronic brain disease that includes memory and language disorders. This disease, which is considered the most common cause of dementia worldwide, accounts for 60-80% of all dementia cases. Recent studies suggest that the cerebellum may play a role in cognitive functions as well as motor functions.

Determination of weight loss methods and effects among wrestlers before an official championship.

Introduction: It is known that combat athletes frequently lose weight before a competition. This study aimed to determine the weight loss methods before an official championship and the effects of these weight loss methods on the performance of wrestlers.

Method: The sample of the study consisted of 350 competitive wrestlers.

["Projet doré": Screening for ocular pathologies in nursing home residents].

For several years, our society has been experiencing an aging of the population. Concurrently, there has been an observable increase in the population of nursing homes (EHPAD). The context of a global epidemic and the public health measures implemented to address it have underscored the vulnerability of our elderly population and the need for remote consultations to ensure continuity of care.

Factors influencing the prescription of add-on long-acting muscarinic antagonists in real-world asthma management: Insights from a national registry.

Current guidelines recommend adding long-acting muscarinic antagonists (LAMAs) in patients with uncontrolled asthma, despite the use of moderate to high doses of inhaled steroid-long-acting beta agonists (ICS/LABA). This study aims to analyze the factors related to the prescription of add-on LAMA in clinical practice for asthma patients, shedding light on physicians' preferences. This study included adult asthma patients on add-on LAMA and ICS/LABA monitored for at least one year in a national registry comprising 2053 asthmatics.

Assessment of heavy metal and radioactive element levels in the ovarian follicular fluid of pregnant and non-pregnant Kyrgyz breed mares.

Objective: In the current study, we aimed to ascertain the levels of heavy metals and radioactive elements in the ovarian follicular fluids of pregnant and non-pregnant Kyrgyz mares.

Materials And Methods: To this end, follicular fluids were obtained from 49 Kyrgyz mares aged 3-5 years. The mares were in various stages of pregnancy (Group 1, 27) or were non-pregnant (Group 2, 22).

Assessment of periodontal dehiscence and fenestration using ultrasonography and cone-beam computed tomography: an in vitro study.

Objectives: This study sought to assess the diagnostic value of ultrasonography (USG) and cone-beam computed tomography (CBCT) for the visibility of periodontal defects.

Materials And Methods: We created 37 periodontal defects (dehiscence and fenestration) in fresh sheep mandibles. Two dentomaxillofacial radiologists assessed the CBCT and ultrasonographic images for the presence of defects.

Extremely low frequency pulsed magnetic field inhibits myocardial damage and apoptosis in rats with CLP-induced sepsis: A histopathological and immunohistochemical evaluation.

We aimed to investigate whether pulsed magnetic fields (PMFs) (1 mT) may have preventive effects on myocardial damage and apoptosis in rats with sepsis. Twenty-eight adult Wistar albino rats were evenly distributed among four experimental groups, each consisting of seven rats: SH, LF-PMF, HF-PMF, and CLP. Sepsis induction was carried out via the cecal ligation and puncture (CLP) method, while rats in the LF-PMF and HF-PMF groups were exposed to 7.

Safety analysis of different ıntensities of elf-pemf in terms of apoptotic, inflammatory, and transcription factor NF-Κb expression levels in rat liver.

Background And Aim: The purpose of this research was to ascertain how exposure to extremely low-frequency pulsed electromagnetic fields (ELF-PEMFs) at varying intensities affects apoptosis-related protein expression levels and liver morphology in rats.

Materials And Methods: In this experimental study, 40 Wistar albino rats were randomly divided into 4 groups, with 10 animals in each group: Control, Sham, 1 milli Tesla (1mT), and 5 mT groups. The control group did not expose any application during the experiment.

Transcriptomic investigation of NP toxicity on HepaRG spheroids.

Metal nanoparticles (NPs) are commonly used nanomaterials, however concerns have been raised about their toxicity. Although a few studies have reported the toxicity of NPs on cells, they have generally been restricted to a limited variety of NPs, inappropriate cell lines, or culture methods. Thus, the adverse effects remain inadequately understood, necessitating further analysis.

Primary cortical cell tri-culture to study effects of amyloid-β on microglia function and neuroinflammatory response.

Background: Microglia play a critical role in neurodegenerative disorders, such as Alzheimer's disease, where alterations in microglial function may result in pathogenic amyloid-β (Aβ) accumulation, chronic neuroinflammation, and deleterious effects on neuronal function. However, studying these complex factors in vivo, where numerous confounding processes exist, is challenging, and until recently, in vitro models have not allowed sustained culture of critical cell types in the same culture.

Objective: We employed a rat primary tri-culture (neurons, astrocytes, and microglia) model and compared it to co-culture (neurons and astrocytes) and mono-culture (microglia) to study microglial function (i.

Oncologic outcomes and trends in each colon cancer location and stages over the last two decades: insights from the SEER registry.

Background: The main purpose of the study is to comprehensively evaluate population-level survival disparities stage-by-stage, according to specific anatomical colon segments, and based on prognosis as defined by lymph nodes among patients who have undergone curative resection for non-metastatic colon cancer.

Methods: The study was conducted from the Surveillance Epidemiology and End Result (SEER) program from the USA. Patients who underwent surgery for colon adenocarcinoma between 2000 and 2019 were identified.

Assessment of non-myelotoxic agents as a preparatory regimen for hematopoietic stem cell gene therapy.

RAG2 deficiency is characterized by a lack of B and T lymphocytes, causing severe lethal infections. Currently, RAG2 deficiency is treated with a Hematopoietic Stem Cell transplantation (HSCT). Most conditioning regimens used before HSCT consist of alkylating myelotoxic agents with or without irradiation and affect growth and development of pediatric patients.

Ferrocene Chalcone Enhanced Cyclotriphosphazene Photodiode Systems via Click Chemistry: Their Synthesis, Electrical, and Photophysical Properties.

In this study, a new ferrocene-decorated cyclotriphosphazene compound () was obtained by the interaction of ferrocene chalcone with azide end groups () and spirophosphazene () bearing alkyne groups using the click method. The structures of all compounds were confirmed using Fourier transform infrared, H, C APT, and P NMR, and MS techniques. The optical band gaps of compounds were measured, showing values of 4.

Bacterial Living Therapeutics with Engineered Protein Secretion Circuits to Eliminate Breast Cancer Cells.

Cancer therapy can be limited by potential side effects, and bacteria-based living cancer therapeutics have gained scientific interest in recent years. However, the full potential of bacteria as therapeutics has yet to be explored due to engineering challenges. In this study, we present a bacterial device designed to specifically target and eliminate breast cancer cells.

Relationship between lower extremity strength asymmetry and linear multidimensional running in female tennis players.

Background: Tennis requires movement abilities in changing playing situations. This article investigates the relationship between lower extremity strength asymmetry ratio and linear and multidimensional running performances in female tennis players.

Methods: A total of 56 female tennis players, with a mean age of 15.

A Study on the Views and Thoughts of Dog Owners in Türkiye on Animal Welfare.

The aim of the present study was to determine the views and thoughts of dog owners in Türkiye on animal welfare. The research material consisted of data obtained from face-to-face surveys with 172 randomly selected dog owners. Half of the dog owners (54,7 %) were aware of the concept of animal welfare, and almost two-thirds (61,6 %) organized their dogs' living spaces according to animal welfare principles.

The Relationship between D'Amico and ISUP Risk Classifications and Ga-PSMA PET/CT SUVmax Values in Newly Diagnosed Prostate Cancers.

Introduction: This study aimed to evaluate the relationship between pathological and clinical risk classifications in newly diagnosed prostate cancer patients, and Ga-PSMA PET/CT data and serum Prostate Specific Antigen (PSA) values.

Method: A total of 203 patients who were diagnosed with prostate cancer between 2019 and 2023, who had not yet received treatment and who underwent Ga-PSMA PET/CT for staging purposes were included in this study.

Results: There was a substantial correlation between D'Amico risk classification, Gleason score, ISUP classification, and the presence or absence of metastasis ( < 0.

An Antibiotic-Degrading Engineered Biofilm Platform to Combat Environmental Antibiotic Resistance.

The presence of antibiotics in natural water bodies is a growing problem regarding the occurrence of antibiotic resistance among various species. This is mainly caused by the excessive use of medical and veterinary antibiotics as well as the lack of effective treatment processes for eliminating residual antibiotics from wastewaters. In this study, we introduce a genetically engineered biomaterial as a solution for the effective degradation of one of the dominantly found antibiotics in natural water bodies.

The Morphometric Analysis of the Ethmoid Roof for Endoscopic Sinus Surgery With Multidetector Computed Tomography.

Most potential major complications in endoscopic sinus surgery are related to the ethmoid bone. To prevent complications, it is necessary to define the concept of a "dangerous ethmoid." The coronal multidetector computed tomography (MDCT) scans of a total of 271 patients, including 101 patients under 18 years old and 170 patients over 18 years old, were examined.

Comparative Evaluation of the Short-Term Outcome of Different Endovascular Aortic Arch Procedures.

: There are several endovascular treatment options to treat aortic arch and thoracic aortic pathologies with custom-made or surgeon-modified aortic stent grafts. This study seeks to assess endovascular treatment methods for aortic arch and thoracic aortic pathologies with no acceptable proximal landing zone for standard thoracic endovascular aortic repair (TEVAR), comparing different treatment methods and evaluating technical success, intraoperative parameters and short-term outcomes. : All patients undergoing elective or emergency endovascular treatment of aortic arch and thoracic aortic pathologies, with no acceptable landing zone for standard TEVAR, between 1 January 2010 and 31 March 2024, at the University Hospital Düsseldorf, Germany were included.