Surgical fear and sleep quality effect the postoperative quality of recovery in patients undergoing brain tumor surgery: cross sectional study.

Background: Patients with a brain tumor experience high levels of anxiety because of the fear of remaining functional and neuropsychological sequelae. This situation affects the postoperative quality of recovery. This study was conducted to determine the effect of surgical fear and sleep quality on the postoperative quality of recovery and pain.

Importance of infarct topography in determination of stroke mechanism and recurrence risk: a post-hoc analysis of the dabigatran acute treatment of stroke trial.

Objective: To evaluate the relationship between infarct pattern, inferred stroke mechanism and risk of recurrence in patients with ischaemic stroke. The question is clinically relevant to optimise secondary stroke prevention investigations and treatment.

Design: We conducted a retrospective analysis of the dabigatran treatment of acute stroke II (DATAS II) trial (ClinicalTrials.

Nanoparticle-assisted plasmonic sensors: Recent developments in clinical applications.

Nanotechnology is an important science that finds a wide range of applications from energy production to industrial production processes and biomedical applications. Nanoparti-cles, which are the most frequently preferred nanomaterials that form the basis of nanotechnolo-gy, are prepared with different composition, size, shape and surface chemistry to provide new techniques in applications in many different fields. The use of nanoparticles in the preparation of plasmonic sensors has increased the interest in plasmonic sensors such as surface plasmon resonance, electrochemical sensors, surface enhanced raman scattering and colorimetric sensors due to their increased sensing capacity on sensor surfaces.

A case report of rare variant: well-developed paracondylar process.

Purpose: The paracondylar process (PCP) is defined as the bony prominence extending from the outer side of the condyles on the outer surface of the occipital bone downwards towards the transverse process of the atlas (TPA). In this case report, the morphometry of the rarely seen PCP and its morphometric data with neighboring structures are evaluated.

Case Report And Results: Unilateral (right-sided) PCP was observed in the cranium of a Caucasian female.

Therapeutic Potential of Stromal Vascular Fraction in Enhancing Wound Healing: A Preclinical Study.

Background: Adipose tissue provides an abundant source of stromal vascular fraction (SVF) cells for immediate administration. It can also give rise to many multipotent adipose-derived stromal cells. SVF is the population of cells obtained from mechanical or enzymatic digestion of lipoaspirate with no necessity for cell culture or expansion.

Effects of robotic surgery experience on open radical prostatectomy results: single centre & single surgeon experience.

This study aimed to evaluate the effect of robotic surgery experience on open radical prostatectomy (ORP) outcomes. We retrospectively reviewed 100 patients who underwent an ORP for clinically localised prostate cancer (PCa) performed by the same experienced surgeon. The groups included the last 50 patients before (Group 1) and the first 50 patients after (Group 2) robotic surgery experience.

Bioenergetic shift and proteomic signature induced by lentiviral-transduction of GFP-based biosensors.

Fluorescent proteins (FPs) stand as pivotal tools extensively employed across diverse biological research endeavors in various model systems. However, long-standing concerns surround their use due to the numerous side effects associated with their expression. Recent investigations have brought to light the significance of hydrogen peroxide (HO) that is associated with the maturation process of green fluorescent protein (GFP) fluorophores.

Synthesis, characterization, and application of novel fluorescent sporopollenin for effective detection of mercury (II) ions from aqueous media.

In this investigation, a novel environmentally friendly functionalized fluorescent Sp-TAB hybrid material was advanced for the sensitive detection of environmentally polluting Hg(II). The characterization of the synthesized fluorescent Sp-TAB hybrid material using SEM and EDX provided insights into morphological and structural changes in the material's pore structure, while XRD and FT-IR analyses revealed the impact of the prepared material at each stage. Optimal parameters such as temperature, contact time, and pH influencing Hg(II) ion detection were determined.

Development of pseudotyped VSV-SARS-CoV-2 spike variants for the assessment of neutralizing antibodies.

Serological studies with pseudotyped viruses offer a safer alternative to live SARS-CoV-2 in evaluating neutralizing antibodies, enabling research in standard labs. The SARS-CoV-2 Spike pseudotyped vesicular stomatitis virus (VSV) pseudoviruses were generated using Spike of Wuhan strain and two variants (B.1.

Detection of mercury(ii) in aqueous media using bodipy-functionalized magnetic fluorescent sporopollenin.

Pollution from heavy metal ions has become a major issue worldwide. Water pollution, particularly with heavy metals like mercury, is a global problem. Developing environmentally friendly, low-cost, high-efficiency, sensitive, and selective sensors for the detection of mercury(ii) ions in aqueous environments has attracted great interest in industry and academia.

The Effect of Glutathione on Development and Prognosis in Non-Muscle-Invasive Bladder Cancer.

Glutathione, along with its related enzymes, constitutes a key antioxidant defense mechanism against oxidative stress and cancer formation in the body. Among urological malignancies, bladder cancer ranks second following prostate cancer. Oxidative stress has significant involvement in the development and prognosis of bladder cancer.

The role of circulating miRNAs in the diagnosis of osteoporosis miRNAs in osteoporosis.

Objective: Osteoporosis, defined as a systemic skeletal disease, is characterized by increased bone fragility and fracture risk. Studies have shown that dysregulation of the functions of miRNAs or the mechanisms they mediate may be an important pathological factor in bone degeneration. Therefore, the aim of the study was to determine the role of miRNAs, which are thought to play a role in bone metabolism, in osteoporosis.

The Mediating Role of Workplace Loneliness in the Effect of Resilience on Work Alienation in Nurses.

The aim of the current research was determining the mediating role of workplace loneliness (WL) in the effect of resilience on work alienation (WA). This study was conducted in Istanbul, Türkiye, between June 2021 and November 2021. Research data were obtained from nurses working in private hospitals operating in Istanbul.

Relationship between NT-proBNP levels and existing/ QRS fragmentation in patients with myocardial infarction.

to assess the evolution of fragmented QRS (fQRS) and NT-proBNP levels during myocardial infarction (MI). Among 511 patients, 205 (40.1%) had fQRS, with 54 (26.

Exposure of antral follicles to medroxyprogesterone acetate during stimulation does not cause molecular perturbations in gonadotropin-responsiveness and steroidogenic function of granulosa cells in progestin-primed cycles.

Study Question: Does medroxyprogesterone acetate (MPA) exposure in progestin-primed ovarian stimulation (PPOS) cycles cause molecular perturbations in the steroidogenic function and gonadotropin responsiveness of the granulosa cells?

Summary Answer: PPOS cycles are identical to traditional GnRH antagonist cycles not only for clinical IVF characteristics but also for gonadotropin receptor expression, response to gonadotropins, and steroidogenic function at the molecular level.

What Is Known Already: PPOS is increasingly used as an alternative to GnRH antagonists due to the inhibitory effect of progesterone on LH release by reducing GnRH pulsatility at the hypothalamic level. Although a growing body of evidence from clinical studies did not indicate significant differences between PPOS and antagonist protocols for IVF cycle characteristics and obstetrical outcomes, it is still unknown whether exposure of the antral follicle cohort to progesterone or its synthetic derivatives during ovarian stimulation causes any subtle molecular aberrations in terms of steroidogenesis and gonadotropin responsiveness.

Therapeutic use of fisetin and pirfenidone combination in bleomycin-induced pulmonary fibrosis in adult male albino rats.

Pulmonary fibrosis is an important health problem; one of the drugs used in its treatment is pirfenidone (PFD). Fisetin (FST) is a flavonoid with antioxidative, anti-inflammatory, and antifibrotic effects. The aim of this study was to induce PF in rats with bleomycin (BLM) and to investigate the combined effect of PFD and FST in the treatment of fibrosis.

What Effects Do Magnetic Fields Exert on the Bioaccumulation of Galanthamine and Lycorine, Growth Efficiency, Capacity to Scavenge Free Radicals, and Defense Enzyme Activities of Summer Snowflakes (Leucojum aestivum L.)?

Leucojum aestivum L. is a bulbous Amaryllidaceae family plant. A pot experiment was conducted to investigate the impact of three different magnetic field (MF) intensities [50, 100 and 150 militesla (mT)] with three different exposure durations (1, 3 and 7 days) on growth parameters, alkaloid levels (galanthamine and lycorine), non-enzymatic antioxidant activities (total phenol-flavonoid content and free radical scavenging activity), and enzymatic antioxidant activities [superoxide dismutase (SOD) and catalase (CAT)] compared with control (no MF) in the bulbs and leaves.

The effect of cone beam computerized tomography voxel size and the presence of root filling on the assessment of middle mesial canals in mandibular molar teeth.

Introduction: The study aims to compare the detection of the middle mesial canal (MMC) in mandibular molar teeth using cone beam computed tomography (CBCT) with different voxel sizes when the mesiobuccal (MB) and mesiolingual (ML) canals have three distinct phases (unpreparation, preparation and obturation and the removal of the obturation and repreparation).

Methods: Two hundred forty-two extracted human mandibular molars were collected and kept in a physiological saline solution prior to use. 0.