Publications by authors named "Buesra Ates"

Background: In triple-negative breast cancer (TNBC) patients receiving adjuvant capecitabine, the impact of HER2 expression on survival outcomes is unclear.

Methods:  Between June 2017 and December 2023, 112 patients with TNBC who received adjuvant capecitabine due to residual masses after neoadjuvant chemotherapy (NACT) in three hospitals were identified. HER2 is analyzed through immunohistochemistry (IHC) and/or in situ hybridization in the core biopsy and/or post-surgical histopathologies.

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Chitosan/oxidized cellulose blended film with Tribulus terrestris (T. terrestris) extract films were successfully produced by casting method. The obtained blend films were characterized by structural, mechanical, optical, permeation, antioxidant, and antimicrobial properties.

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Noise pollution has become an important type of environmental pollution, especially in populated areas, due to changes in transportation preferences and industry development. The World Health Organization reports that noise, along with air and water pollution, poses one of the most dangerous pollution threats in big cities. In this study, noise pollution measurements were carried in two different regions of a major city, focusing on sensitive points such as hospitals and schools.

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Background: Conscientious objection poses ethical dilemmas frequently encountered by nurses, allowing them to prioritize personal beliefs in caregiving. However, it may also be viewed as a stance jeopardizing patients' healthcare access. There is no measurement tool to measure conscientious objection in nurses.

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Introduction: The positive effect of varicocelectomy on sperm parameters (sperm morphology, concentration, motility) and fertility and pregnancy rates has been proven. Although various techniques have been defined for varicocele treatment, varicocelectomy with the pulling technique was first defined in 2017. The aim of this retrospective study is to compare the effectiveness and reliability of subinguinal microsurgical varicocelectomy with the "pulling" technique and conventional subinguinal varicocelectomy.

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Objective: Transcutaneous electrical nerve stimulation (TENS) has been applied to alleviate post-thoracotomy pain. In this study, we investigated the effects of TENS on pain scores, additional opioid doses, opioid-related side effects, and potential respiratory and cardiac complications.

Method: In this controlled, randomized study, 40 patients underwent muscle-sparing thoracotomy.

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In recent years, the role of functional foods in addressing various health issues, including cancer, has gained significant attention. Among these, the cytotoxic and apoptotic properties of Malatya apricots hold particular interest for their potential therapeutic benefits. This study focused on exploring the effects of methanol and acetone extracts from four popular Malatya apricot varieties-Hacıhaliloğlu, Hasanbey, Kabaaşı, and Soğancı-on cancer cell lines.

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To compare the predictive effects of stone size and volume on the efficacy and safety of retrograde intrarenal surgery (RIRS) and to determine the cutoff values of stone volume for prediction of RIRS efficacy and safety. Patients who underwent RIRS between 2017 and 2021 in six referral centers were retrospectively included in the study. The database of the RIRsearch group, which was formed prospectively, was used for this retrospective analysis.

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Background: Hallux valgus correction is mostly done by metatarsal procedures, and widely accepted strategy is to decide which surgical method should be used is based on radiological severity using intermetatarsal (IMA) and hallux valgus (HVA) angles (classical angular correction approach-CACA). The aim of the study is to compare the postoperative improvement in radiographic parameters and morphologic appearance of the foot between patients operated with and without adhering to CACA strategy based on classical severity classification using angle measurements.

Materials And Methods: A retrospective comparative study between two groups (conforming and not conforming to proposed algorithm) was performed.

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Background: Nutritional profiles and guidelines are determined by various associations to ensure optimum health of cats and provide pet food manufacturers nutritional recommendations to ensure the well-balanced and nutritionally adequate pet food.

Objectives: It was aimed to determine some trace elements and macro minerals in prescription and non-prescription dry cat foods and compare the contents with the suggested guidelines to evaluate the potential in-compliance.

Methods: A total of 96 dry cat foods were evaluated.

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BACKGROUND Shiga toxin-producing Escherichia coli (STEC) causes serious bacterial illnesses from consuming undercooked meat and foods contaminated with feces. This study aimed to describe the characteristics of an STEC outbreak associated with hemolytic uremic syndrome (HUS) that emerged in Turkey and affected 21 adults. MATERIAL AND METHODS The medical records of 21 adult patients who were admitted to Ankara Bilkent City Hospital Internal Medicine Intensive Care Department with the diagnosis of HUS between July and September 2022 were retrospectively evaluated through the system.

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Aim: This study aimed to investigate the relationship between electrophysiological findings of diabetic neuropathy (DN) and patients' quality of life, neuropathic pain levels, and well-being.

Materials And Methods: A cross-sectional study was conducted in 12 centers in Turkey. DN patients were categorized into four stages based on electrophysiological findings using the Baba classification.

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Article Synopsis
  • Wearable sensors in healthcare enable continuous and minimally invasive monitoring of health, providing detailed physiological data for better clinical understanding.
  • The next generation of these devices expands beyond biophysical measurements to include biochemical monitoring of substances in various body fluids like sweat and saliva.
  • For widespread adoption, these wearable devices need large-scale validation, ethical considerations, and acceptance among different user groups, as well as support for reimbursement and public health initiatives.
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  • This study focuses on the role of Thyroid Transcription Factor-1 (TTF-1) in lung adenocarcinoma (LUAD) brain metastases, specifically its predictive value and relationship with patient outcomes.
  • Researchers analyzed data from 245 patients who had brain metastases, looking at factors like tumor volume and survival rates based on TTF-1 expression status.
  • Results indicate that TTF-1 negative patients had larger tumors, higher proliferation rates, and worse survival outcomes, suggesting that TTF-1 negativity signifies a more aggressive form of the disease, warranting further study on its underlying mechanisms.
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Knowing the concentration levels of phenolic compounds and anthocyanins in grape berries plays a key role, as these compounds significantly contribute to the nutritional value and quality of grapes, affecting both health benefits and grape quality. The current study was conducted to investigate how different tillage (disc harrow, chisel, no tillage) and organic fertilizer (Antep radish and broccoli chopped residue, olive blackwater) treatments affect the concentration of these valuable compounds in Royal grape berries over three consecutive years (2020-2022), providing insights into optimal agricultural practices for enhancing grape quality. Our results documented significant variations in phenolic and anthocyanin concentrations across different soil tillage, organic fertilizer treatments and years.

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Tartrazine, an azo dye prevalent in pharmaceuticals and food items, was investigated for its impact on fetal development, specifically examining visceral and skeletal abnormalities in rat offspring exposed to daily oral doses throughout pregnancy. Fourteen pregnant rats were randomly assigned to control and tartrazine groups (seven animals each), with tartrazine administered via oral gavage at 7.5 mg/kg throughout gestation.

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Objective: Obesity and diabetes mellitus (DM) are major risk factors for osteoarthritis (OA), but it remains unclear how comorbidity affects apoptosis signaling in OA. This study investigated the effect of metabolic diseases on apoptosis and apoptosis-related intracellular and extracellular signaling in OA.

Methods: Excision materials of human articular cartilage from total knee arthroplasties were collected.

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Article Synopsis
  • Dual antiplatelet therapy (DAPT) is essential for managing acute and chronic coronary syndromes, helping to lower mortality rates and prevent further complications.
  • A study followed 1500 patients on a specific fixed-dose DAPT (ASA + clopidogrel) to evaluate its effectiveness and safety, primarily focusing on hospitalization and bleeding risks.
  • Results indicated that the fixed-dose combination therapy was effective, with low rates of hospitalization for cardiovascular issues and minimal bleeding complications in appropriately selected patients.
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Article Synopsis
  • - Sepsis is a serious condition characterized by inflammation and cell death, often leading to multiple organ failure, requiring quick medical attention; lipopolysaccharide (LPS) triggers inflammatory responses through specific receptors like TLR-2.
  • - The study explores the role of melatonin (MEL) in reducing lung injury caused by LPS-induced septic shock in rats, highlighting its potential to lower the expressions of inflammatory markers NEK7, TLR2, and NLRP3.
  • - Results showed that melatonin treatment reduced lung tissue damage, cell infiltration, and wall thickening, indicating that it may provide therapeutic benefits in managing sepsis-related acute lung injury.
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: The data on acute cholangitis in the octogenarian population are very limited. This study aimed to examine the clinical characteristics of acute cholangitis and complications related to endoscopic retrograde cholangiopancreatography (ERCP) in octogenarians. : This study was conducted prospectively between July 2022 and December 2023 and included 250 patients aged 65 years and older.

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Objectives And Background: Our objective was to determine the diagnostic significance of a low T-wave amplitude (TWA) and T/R ratio, defined as the amplitude ratio between the T waves and the R waves, in patients with acute non-ST elevation myocardial infarction (ANSTEMI). Syntax score (SS) shows the extension of coronary artery disease. Previously, low TWA and T/R ratios were demonstrated to be inversely proportional to the risk of sudden cardiac arrest in different cardiac disease conditions.

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We investigate silicon waveguides with subwavelength-scale modulation for applications in free-electron-photon interactions. The modulation enables velocity matching and efficient interactions between low-energy electrons and co-propagating photons. Specifically, we design a subwavelength-grating (SWG) waveguide for interactions between 23-keV free electrons and ≈1500-nm photons.

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Purpose: Additive manufacturing (AM) technologies are used to fabricate 3D-printed provisional dental restorations. The purpose of this study was to investigate the flexural strength of 3D-printed resins and compare their mechanical performance with those of conventional resins indicated for provisional restorations.

Materials And Methods: This study included six different 3D-printed resin materials, namely (Nextdent (ND); Temp PRINT (TP); Optiprint temp (OT); 3Delta Etemp (DE); Saremco print | CROWNTEC (SA); MED690 (ST)), and one conventional (Protemp (PT)) (Control) provisional resin material.

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Objective: The post-operative analgesic efficacy of transversalis fascia plane (TFP) block is controversial in pediatric patients undergoing herniotomy. This study aims to compare the efficacy of TFP block and standard analgesic methods.

Methods: Sixty patients aged 1-8 years who underwent the open procedure of herniotomy were randomly divided into two groups TFP block (n = 30) or control group (n = 30).

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Objectives: This clinical trial aimed to evaluate the clinical outcomes of 3D-printed resin composite posterior fixed dental prosthesis (FDP) restorations.

Materials And Methods: Between October 2020 and August 2022, 49 patients (33 females, 16 males, aged 19-60) received 68 3-unit 3D-printed resin composite posterior FDPs (ELS Even Stronger, Saremco, Switzerland). Follow-ups were conducted at baseline (2 weeks) by independent observers using modified FDI criteria, assessing anatomical form, marginal adaptation, surface roughness, color match, fracture, retention, and patient feedback.

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