Combination of lead-field theory with cardiac vector direction: ECG imaging of septal ventricular activation.

Background: Despite the tremendous progress recently reported in ECG imaging (ECGI), some fundamental challenges are still hindering this non-invasive technology from meeting rising clinical expectations. In the present work, we address one of the major ECGI shortcomings in reconstruction of ventricular activation - the limited accuracy of endocardial and particularly septal mapping.

Methods: Ten CRT patients (five female, median (min-max) age - 61 (27-78) years) with previously implanted CRT devices underwent ECGI with isolated right ventricular (RV) pacing.

[Automatic detection of ventricular and supraventricular wide QRS arrhythmias using complex of morphological criteria and algorithms].

Aim: The aim of study is a detection of ventricular and supraventricular wide QRS arrhythmias using complex of morphological criteria and algorithms by method of automatic analysis.

Materials And Methods: For 100 patients (m/f - 61/39, Me (min; max) - 44.5 (10; 85) years) of researched group the analysis of 14306 single wide ectopic complexes (QRS 120-230 ms) has been done.

ECG Adapted Fastest Route Algorithm to Localize the Ectopic Excitation Origin in CRT Patients.

Although model-based solution strategies for the ECGI were reported to deliver promising clinical results, they strongly rely on some a priori assumptions, which do not hold true for many pathological cases. The fastest route algorithm (FRA) is a well-established method for noninvasive imaging of ectopic activities. It generates test activation sequences on the heart and compares the corresponding test body surface potential maps (BSPMs) to the measured ones.

First-in-Man Analysis of the Relationship Between Electrical Rotors From Noninvasive Panoramic Mapping and Atrial Fibrosis From Magnetic Resonance Imaging in Patients With Persistent Atrial Fibrillation.

Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging can be used to evaluate characteristics of atrial fibrosis. The novel noninvasive epicardial and endocardial electrophysiology system (NEEES) allows for the identification of sources with rotor activity. This study describes a new technique to examine the relationship between rotors and LGE signal intensity in patients with persistent atrial fibrillation (PERS) scheduled for ablation.

[Noninvasive Electrophysiological Mapping in Patients With Complete Left Bundle Branch Block and Different Modes of Biventricular Pacing].

Objective: to investigate possibilities of noninvasive electrophysiological mapping (NEM) during biventricular (BiV) pacing and to compare the results with data of 12 lead ECG and tissue Doppler echocardiography (TDI).

Material And Methods: The study included 25 patients with complete left bundle branch block (LBBB) and implanted cardiac resynchronization therapy (CRT) system. Twenty-two patients were CRT responders, three other patients did not demonstrate a clear effect.

Serum trace elements are associated with hemostasis, lipid spectrum and inflammatory markers in men suffering from acute ischemic stroke.

The primary objective of the study is investigation of the association between trace elements status and hemostasis, lipid spectrum and inflammatory markers in acute ischemic stroke (AIS). A total of 30 men suffering from AIS and 30 healthy controls were involved in the current survey. Blood count, serum lipid spectrum, complement components C4 and C3a, vascular endothelial growth factor (VEGF), S100B protein, NR2 antibodies (NR2Ab), and total antioxidant status (TAS), as well as plasma fibrinogen, and D-dimer levels and activated partial thromboplastin time (APTT) were assessed.

Serum trace elements are interrelated with hormonal imbalance in men with acute ischemic stroke.

Unlabelled: The objective of the present study was to assess hormonal and trace element status in men suffering from acute ischemic stroke.

Methods: 21 acute ischemic stroke patients and 21 age- and body mass index-matched healthy volunteers were enrolled in the study. Serum trace elements were assessed using inductively coupled plasma mass spectrometry.

Ventricular tachycardia as the first manifestation of Churg-Strauss syndrome.

Life-threatening arrhythmias are often found in heart diseases, but they are rare as clinical symptoms of Churg-Strauss syndrome. We report a case of a 66-year-old woman with symptomatic monomorphic ventricular tachycardia as the first sign of Churg-Strauss syndrome. Cardiac manifestations were the main clinical symptoms of the disease, and changes in other organs were weakly expressed.

Serum Trace Element Profiles, Prolactin, and Cortisol in Transient Ischemic Attack Patients.

The primary aim of the present study was to assess the association between trace element status, brain damage biomarkers, cortisol, and prolactin levels in transient ischemic attack (TIA) patients. Ten male and 10 female TIA patients were involved in this study. Age, gender, and BMI-matched volunteers served as the respective control group.

[Differential radiation diagnosis of microcalcinates grouped in breast].

A complex methods was used to examine 39 females with the microcalcinates grouped in the breast. The diagnostic efficiency of a number of mammographic and sonographic signs was comparatively evaluated. Ultrasonography was shown to be advisable in differentially diagnosing cancer and sclerosing adenosis.