Publications by authors named "Buckland A"

Article Synopsis
  • - This study investigated the effectiveness of combining habit reversal therapy (HRT) with acceptance and commitment therapy (ACT) for reducing tic severity in adults with Tourette's syndrome.
  • - Participants were assessed for tic severity at multiple points (baseline, post-treatment, 6 months, and 12 months) using the Yale Global Tic Severity Scale (YGTSS) and video evaluations, demonstrating significant reductions in tics.
  • - The results indicate that the HRT + ACT approach not only effectively lowered tic severity following treatment but also maintained these improvements for up to 12 months, suggesting it's worth exploring further in comparison to HRT alone.
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Article Synopsis
  • The study investigates the safety of accessing the L4-5 disc level in the lumbar spine using two different patient positions: lateral decubitus (LAT) and supine (SUP).
  • It involves a retrospective analysis of 140 patients, where LAT patients had significantly more additional lateral lumbar interbody fusion procedures and surgeries for spinal deformity compared to SUP patients.
  • Results show that while intraoperative complications were similar, LAT patients experienced significantly fewer postoperative complications, including a notable reduction in postoperative ileus.
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Article Synopsis
  • Mitochondrial donation is now legally allowed in Australia to help prevent the passing of mitochondrial diseases from mothers to their children as part of a clinical trial.
  • A systematic literature review analyzed five cohort studies and 19 case reports on how mitochondrial disease affects pregnancy.
  • While many women with mitochondrial disease experience no negative health effects during pregnancy, there is a risk of serious complications, leading to proposed guidelines for preconception counseling and antenatal care.
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Background: Percutaneous pedicle screw (PPS) placement has become a pivotal technique in spinal surgery, increasing surgical efficiency and limiting the invasiveness of surgical procedures. The aim of this study was to analyze the accuracy of computer-assisted PPS placement with a standardized technique in the lateral decubitus position.

Methods: A retrospective review of prospectively collected data was performed on 44 consecutive patients treated between 2021 and 2023 with lateral decubitus single-position surgery.

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Introduction: Following the COVID-19 pandemic and ongoing pressures within the National Health Service, there has been an increasing concern about the well-being of junior doctors in the UK. Newly qualified doctors are particularly vulnerable due to the significant shift in responsibility they experience.

Objectives: To implement peer-led reflective session for foundation year 1 (FY1) (first-year postgraduation) doctors and to create a dedicated space in which doctors could share difficult or challenging experiences.

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Background Context: Academic orthopedic journals and specialty societies emphasize the importance of two-year follow-up for patient-reported outcome measures (PROMS) after spine surgery, but there are limited data evaluating the appropriate length of follow-up.

Purpose: To determine whether PROMs, as measured by the Oswestry Disability Index (ODI), would change significantly after 2-months postoperatively after lumbar decompression surgery for disc herniation or spinal stenosis.

Study Design: Retrospective analysis of prospectively and consecutively enrolled patients undergoing lumbar decompression surgery between 2020 and 2021 from a single surgeon spine registry.

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Background: Recombinant human bone morphogenetic protein 2 (rhBMP-2, or BMP for short) is a popular biological product used in spine surgeries to promote fusion and avoid the morbidity associated with iliac crest autograft. BMP's effect on pseudarthrosis in transforaminal lumbar interbody fusion (TLIF) remains unknown.

Objective: To assess the rates of pseudarthrosis in single-level TLIF with and without concurrent use of BMP.

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Introduction: The National Physical Therapy Examination (NPTE) is a standardized examination designed to assess competence after graduation from an entry-level physical therapist education program.

Review Of Literature: Previous studies have identified applicant and student variables that are related to NPTE performance, with applicant variables reflecting performance before admission and student variables reflecting performance after admission. However, there are very few articles describing how these variables can be combined to predict NPTE performance.

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Background: Myelin oligodendrocyte glycoprotein (MOG) IgG seropositivity is a prerequisite for MOG antibody-associated disease (MOGAD) diagnosis. While a significant proportion of patients experience a relapsing disease, there is currently no biomarker predictive of disease course. We aim to determine whether MOG-IgG epitopes can predict a relapsing course in MOGAD patients.

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Background: Minimally invasive surgical transforaminal lumbar interbody fusion (MIS-TLIF) is an increasingly common procedure for the treatment of lumbar degenerative pathologies. The MIS-TLIF technique often results in less soft-tissue injury compared with the open TLIF technique, reducing postoperative pain and recovery time. However, the narrow surgical aperture of this minimally invasive technique has increased the difficulty of interbody cage placement.

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Aims: The aim of this study was to reassess the rate of neurological, psoas-related, and abdominal complications associated with L4-L5 lateral lumbar interbody fusion (LLIF) undertaken using a standardized preoperative assessment and surgical technique.

Methods: This was a multicentre retrospective study involving consecutively enrolled patients who underwent L4-L5 LLIF by seven surgeons at seven institutions in three countries over a five-year period. The demographic details of the patients and the details of the surgery, reoperations and complications, including femoral and non-femoral neuropraxia, thigh pain, weakness of hip flexion, and abdominal complications, were analyzed.

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Background: More than 28 million people in the United States visited their dentists but not a physician in 2018, yet only a few states allow dentists to administer vaccines to patients, and those vaccines are limited to influenza, COVID-19, and human papillomavirus.

Methods: To assess the receptiveness of adult dental patients and caregivers of pediatric dental patients to receive necessary vaccines during their dental appointment, a survey was distributed to patients attending a dental visit at a rural federally qualified health center from June 28, 2021, through December 31, 2021.

Results: Among the responses from 643 adult patients and 625 pediatric caregivers, approximately one-half (54.

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Introduction: The term "spinopelvic mobility" is most often applied to motion within the spinopelvic segment. It has also been used to describe changes in pelvic tilt between various functional positions, which is influenced by motion at the hip, knee, ankle and spinopelvic segment. In the interest of establishing a consistent language for spinopelvic mobility, we sought to clarify and simplify its definition to create consensus, improve communication, and increase consistency with research into the hip-spine relationship.

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Introduction: As of October 26, 2022, only 9% of children in the United States aged 6 months to 4 years have received at least one dose of COVID-19 vaccine despite FDA approval since June 17, 2022. Rates are better yet still low for children aged 5 to 11 years as nearly 30% were fully vaccinated as of August 23, 2022. Vaccine hesitancy among adults is one of the major factors affecting low vaccine uptake rates in children against COVID-19, yet most studies examining vaccine hesitancy have targeted school-age and adolescent children.

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Study Design: Multi-centre retrospective cohort study.

Objective: To evaluate the feasibility and safety of the single-position prone lateral lumbar interbody fusion (LLIF) technique for revision lumbar fusion surgery.

Background Context: Prone LLIF (P-LLIF) is a novel technique allowing for placement of a lateral interbody in the prone position and allowing posterior decompression and revision of posterior instrumentation without patient repositioning.

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Article Synopsis
  • The study investigated the clinical outcomes, fusion rates, and complications of lateral lumbar interbody fusion (LLIF) in Australia, focusing on the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) compared to other graft materials.
  • It involved a retrospective analysis of 343 patients operated on between 2011 and 2021, with significant improvements observed in patient-reported outcomes and a total complication rate of 15%.
  • Results showed that rhBMP-2 led to higher fusion rates at both 6 and 12 months, suggesting its superiority over non-rhBMP-2 grafts without increasing complication rates.
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Article Synopsis
  • Complex spinal surgeries for adults can lead to high complication rates; a multidisciplinary case conference was introduced to improve patient selection and surgical outcomes.
  • A study analyzed 263 patients, comparing those who underwent surgery before and after the introduction of the conference, focusing on complications and reoperations.
  • Results showed that patients treated after the conference were older, had lower blood loss, and experienced significantly fewer complications during surgery compared to those treated before the conference.
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Background: Identify the external applicability of the American College of Surgeons' National Surgical Quality Improvement Program (NSQIP) risk calculator in the setting of adult spinal deformity (ASD) and subsets of patients based on deformity and frailty status.

Methods: ASD patients were isolated in our single-center database and analyzed for the shared predictive variables displayed in the NSQIP calculator. Patients were stratified by frailty (not frail <0.

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Background Context: The advantages of lateral single position surgery (LSPS) in the perioperative period has previously been demonstrated, however 2-year postoperative outcomes of this novel technique have not yet been compared to circumferential anterior-posterior fusion (FLIP) at 2-years postoperatively.

Purpose: Evaluate the safety and efficacy of LSPS versus gold-standard FLIP STUDY DESIGN/SETTING: Multicenter retrospective cohort review.

Patient Sample: Four hundred forty-two patients undergoing lumbar fusion via LSPS or FLIP OUTCOME MEASURES: Levels fused, operative time, estimated blood loss, perioperative complications, and reasons for reoperation at 30-days, 90-days, 1-year, and 2-years.

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Objective: The BEACON CRC randomised controlled trial (NCT02928224) in BRAF-mutant metastatic colorectal cancer (mCRC) patients showed improved overall survival for the combination treatment of encorafenib (BRAF inhibitor) with cetuximab (EGFR inhibitor) compared with cetuximab with chemotherapy (FOLFIRI (folinic acid, fluorouracil and irinotecan) or irinotecan). We aimed to evaluate the cost-effectiveness of encorafenib with cetuximab in adult patients with BRAF-mutant mCRC after prior systemic therapy, from the perspective of the French healthcare system.

Design: A partitioned survival analysis model was developed to assess the cost-effectiveness of encorafenib with cetuximab using data from BEACON CRC (encorafenib with cetuximab and cetuximab with FOLFIRI or irinotecan).

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Accurate and reproducible acetabular component positioning is among the most important technical factors affecting outcomes of total hip arthroplasty. Although several studies have investigated the influence of pelvic tilt and obliquity on functional acetabular anteversion, the effect of pelvic axial rotation has not yet been established. We analyzed a generic simulated pelvis created using preoperative full-body standing and sitting radiographs.

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Study Design: Retrospective analysis of outcomes in cervical spine and shoulder arthroscopy patients.

Objective: The objective of this study is to assess differential improvements in health-related quality of life for cervical spine surgery compared with shoulder surgery.

Summary Of Background Data: An understanding of outcome differences between different types of orthopedic surgeries is helpful in counseling patients about expected postoperative recovery.

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Purpose: To provide definitions and a conceptual framework for single position surgery (SPS) applied to circumferential fusion of the lumbar spine.

Methods: Narrative literature review and experts' opinion.

Results: Two major limitations of lateral lumbar interbody fusion (LLIF) have been (a) a perceived need to reposition the patient to the prone position for posterior fixation, and (b) the lack of a robust solution for fusion at the L5/S1 level.

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Article Synopsis
  • This study reviews patients who underwent surgery at a single medical institution to assess a new way to detect pseudarthrosis using dynamic radiographs.* -
  • A traditional method relies on measuring interspinous motion (ISM) differences, while a novel angular method utilizes angles between spinous processes, avoiding the need for complicated calibrations.* -
  • The findings showed a strong correlation between the two methods, with both achieving high sensitivity and specificity for detecting pseudarthrosis confirmed by CT scans, indicating the angular method could be a reliable alternative.*
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