Publications by authors named "Bu-Yu Zhou"

Published data on the association between CYP3A4*1B polymorphism and cancer risk are inconclusive. To derive a more precise estimation of the association, we conducted a meta-analysis. A systematic search of the PubMed database was performed.

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Background: Approximately 2 million doses of vaccine against haemorrhagic fever with renal syndrome (HFRS) have been used annually in China. However, there were limited studies focused on persistence of immune responses to HFRS vaccine in healthy adults. A phase 4, multicentre, open trial has been undertaken to assess antibody persistence after HFRS vaccination of healthy adolescents and adults aged 16-60 years.

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Article Synopsis
  • China has the highest rates of hemorrhagic fever with renal syndrome (HFRS), making up 90% of global cases, but the longevity of anti-hantavirus antibodies in patients and vaccinated individuals is unclear.
  • A study involving 600 participants measured anti-hantavirus IgG antibodies in HFRS patients, vaccinated individuals, and control groups, revealing significant differences in antibody levels among these groups.
  • The findings indicate that HFRS patients may develop long-lasting immunity and suggest that vaccination could effectively stimulate the production of antibodies against the virus.
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