Quick and Accurate Placement of Cannulated Screws to Internal Fixation of Femoral Neck Fractures Using a Novel Guide Device.

Introduction: Fixation of femoral neck fractures with cannulated screws is an accepted method. This study aimed to compare a novel guide device and conventional technique with regard to the accuracy, operation time, fluoroscopy numbers, and drilling attempts during the insertion of cannulated screws to internal fixation of femoral neck fractures.

Methods: This retrospective study included 60 patients with intracapsular femoral neck fractures who were treated with cannulated screws from January 2020 to June 2021.

Hypoxia regulation of facilitated glucose transporter-1 and glucose transporter-3 in mouse chondrocytes mediated by HIF-1alpha.

Objectives: Chondrocytes reside in a hypoxic environment; they utilize glucose as the main energy source. Facilitated glucose transport represents the first rate-limiting step in glucose metabolism.

Results: Here we demonstrated that hypoxia induced an elevated expression level of GLUT-1 and -3 in chondrocytes.