[Occurence, etiology and clinical significance of trombocytopenia in pregnancy].

Objective: The principal objective of the study is to compare results from the experimental group of pregnant women suffering from thrombocytopenia in pregnancy with results from the control group of pregnant women with normal physiologic blood platelet count.

Setting: Department of Obstetrics and Gynaecology of the Tomas Bata Regional Hospital Zlín, Obstetrics and Gynaecology Clinic, Haematology and Oncology Clinic of the Palacky University Teaching Hospital and Medical School in Olomouc, Obstetrics and Gynaecology Clinic of the Ostrava Teaching Hospital.

Methodology: A group of 200 pregnant women suffering from thrombocytopenia underwent thorough medical tests.

[Preeclampsia and thrombin generation test].

Objective: Acquiring new information to allow prediction of the development of diseases associated with impaired coagulation. Design effective preventive measures most serious diseases (TEN) in the fields of gynecology and obstetrics. For pregnant women with preeclampsia, hypertension compared with women with normal pregnancies could lead to increased thrombin generation due to the synergistic effect of thrombotic risk factors.

[Endotelial activation markers--possibilities of their detection and clinical signification in gynaecology and obstetric].

Objective: Summary of the current knowledge of the role of endotelial activation markers in the pathogenesis of the selected diseases and high-risk pregnancy.

Design: Review article.

Methods: Compilation of the published data from scientific literature.