Publications by authors named "Bryce J Laurin"
Article Synopsis
- Glioblastoma multiforme (GBM) is the most aggressive brain tumor but rarely spreads outside the central nervous system, with only 0.4% of cases showing metastasis, possibly influenced by genetic mutations.
- A systematic review analyzed 357 studies and 211 patients, revealing that 36.9% of metastases were found near surgical sites and common metastasis locations included bone, lung, and lymph nodes.
- Unique genetic mutations were observed in primary GBM and metastatic lesions, suggesting that understanding these changes could explain how GBMs spread beyond the CNS and aid future treatment strategies.
Background: Standard of care for brain metastases involves stereotactic radiosurgery (SRS). For cases that also require surgery because of lesion size, edema, or neurological symptoms, whether to provide pre- or postoperative SRS has become a prevalent debate.
Observations: Herein, the unique case of a patient with brain metastases of the same pathology and similar size in two different brain locations at two different times is described.