Synthesis and crystal structure of sodium (ethane-1,2-di-yl)bis-[(3-meth-oxy-prop-yl)phosphinodi-thiol-ate] octa-hydrate.

The title compound, -poly[[tri-aqua-sodium]-di-μ-aqua-[tri-aqua-sodium]-μ-(ethane-1,2-di-yl)bis-[(3-meth-oxy-prop-yl)phosphinodi-thiol-ato]], [Na(CHOPS)(HO)] , crystallizes in the triclinic space group 1. The dianionic [CHO(CH)P(=S)(S-)CHCHP(=S)(S-)(CH)OCH] ligand fragments are joined by a dicationic [Na(HO)] cluster that includes the oxygen of the meth-oxy-propyl unit of the ligand to form infinite chains.

Combinatorial design of multimeric chelating peptoids for selective metal coordination.

Current methods for metal chelation are generally based on multidentate organic ligands, which are generated through cumbersome multistep synthetic processes that lack flexibility for systematically varying metal-binding motifs. Octadentate ligands incorporating hydroxypyridinone or catecholamide binding moieties onto a spermine scaffold are known to display some of the highest affinities towards f-elements. Enhancing binding affinity for specific lanthanide or actinide ions however, necessitates ligand architectures that allow for modular and high throughput synthesis.

Synthesis of tetraphosphine macrocycles using copper(i) templates.

The synthesis of phosphine macrocycles is a relatively underdeveloped area and no standard synthetic routes have emerged. Accordingly, two general synthetic routes to tetradentate phosphine macrocycles were investigated. Both routes use Cu(i) ions as template ions because, unlike other metals such as Pd(ii) and Pt(ii), the Cu(i) ions can be removed from the macrocyclic complex without degrading the macrocycle ligand.

A facile route to old and new cyclophanes via self-assembly and capture.

Cyclophanes are a venerable class of macrocyclic and/or cage compounds that often feature high strain, unusual conformations and quite surprising properties, many of which are legendary in physical organic chemistry. However, the discovery of new, diverse cyclophanes and derivatives has been hindered by syntheses that are traditionally low-yielding, requiring long reaction times, laborious purification steps and often extreme conditions. Herein, we demonstrate a new self-assembly route to a variety of discrete cyclic and caged disulfide structures, which can then be kinetically captured upon sulfur extrusion at room temperature to give a diversity of new thioether (hetera)cyclophanes in high yield.

P,P'-Diphenyl-ethyl-enediphosphinic acid dihydrate.

The title compound, C(14)H(16)O(4)P(2)·2H(2)O, possesses a crystallographic inversion center where two -P(=O)(OH)(C(6)H(5)) groups are joined together via two -CH(2) groups. In the crystal, the acid molecules are linked by the water molecules via O-H⋯O hydrogen bonds, leading to the formation of a two-dimensional network lying parallel to (101).