In vitro injection of osteoporotic cadaveric femurs with a triphasic calcium-based implant confers immediate biomechanical integrity.

Current pharmaceutical therapies can reduce hip fractures by up to 50%, but compliance to treatment is low and therapies take up to 18 months to reduce risk. Thus, alternative or complementary approaches to reduce the risk of hip fracture are needed. The AGN1 local osteo-enhancement procedure (LOEP) is one such alternative approach, as it is designed to locally replace bone lost due to osteoporosis and provide immediate biomechanical benefit.

Radiographic measurement of anterior talar translation in the ankle: determination of the most reliable method.

Background: Although most would agree that stress radiography is an important research tool to evaluate the integrity of the ankle ligaments in studies of chronic ankle instability, there is little agreement with regard to the best technique to make these measurements. The primary objective of this study was to establish the most reliable method for measuring anterior displacement of the talus relative to the tibia using stress radiographs of the ankle. This information is necessary to standardize radiographic evaluation of injured ankles and for biomechanical studies of the ankle joint, but has never been investigated.