Publications by authors named "Bryan Lucero"
BMC Genomics
October 2017
Article Synopsis
- Tuberculosis (TB) is a significant global health issue, with drug resistance, especially to Pyrazinamide (PZA), complicating treatment efforts.
- Researchers analyzed 68 M. tuberculosis strains from TB patients in Peru, identifying no clear genetic clustering but discovering mutations in the pncA gene and other novel genes linked to PZA resistance.
- These findings indicate that PZA resistance may involve multiple mechanisms, suggesting that the drug targets several biological pathways instead of just one.
