Publications by authors named "Bryan Hedgpeth"

Environmental risk assessments of very hydrophobic organic compounds (VHOCs) in soils are often difficult because multiple processes (e.g., sorption, volatilization, biodegradation) can complicate the interpretation of results.

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Reliable delineation of aquatic toxicity cut-offs for poorly soluble hydrocarbons is lacking. In this study, vapor and passive dosing methods were applied in limit tests with algae and daphnids to evaluate the presence or absence of chronic effects at exposures corresponding to the water solubility for representative hydrocarbons from five structural classes: branched alkanes, mono, di, and polynaphthenic (cyclic) alkanes and monoaromatic naphthenic hydrocarbons (MANHs). Algal growth rate and daphnid immobilization, growth and reproduction served as the chronic endpoints investigated.

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Article Synopsis
  • - Drug-ethanol interactions can lead to liver damage, particularly when acetaminophen and ethanol are taken together, as this can overload the liver's ability to process these substances.
  • - The combination of ethanol and acetaminophen can increase the activity of enzymes that generate harmful compounds in the liver while depleting protective substances, leading to potential toxicity.
  • - A study utilized various bioinformatics tools to analyze the metabolic pathways involved in the ethanol-acetaminophen interaction, but it highlighted the need for more data to confirm direct effects and emphasized the importance of multiple software applications for assessing such interactions.
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  • The OECD test guideline 236 assesses fish embryo acute toxicity using four main indicators (coagulation, somite formation, tail-bud detachment, heartbeat) with zebrafish embryos as subjects.
  • This study analyzed additional sublethal effects after exposing zebrafish embryos to seven different petroleum products, finding significant issues like pericardial edema and low embryo viability.
  • The research highlights the usefulness of a new analytical method, BE-SPME, to measure substance concentrations and predict sublethal toxicity in embryos beyond what the traditional guideline covers.
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Extracting and identifying genetic material from environmental media (i.e. water and soil) presents a unique opportunity for researchers to assess biotic diversity and ecosystem health with increased speed and decreased cost as compared to traditional methods (e.

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Estuarine fish in the northern Gulf of Mexico are exposed annually to hypoxic conditions. In addition to hypoxia, fish located throughout the northern Gulf of Mexico were potentially exposed to oil released during the Deepwater Horizon incident. Therefore, the interaction between oil exposure and hypoxia is worth investigating.

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