Publications by authors named "Bruno T Fortuna"
Front Cell Dev Biol
March 2022
Article Synopsis
- Mitochondria are crucial organelles whose structure influences cell functions, and their remodeling affects immune responses, particularly in eosinophils, though knowledge on this is limited.*
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- Using advanced imaging techniques, researchers found that during eosinophil development, mitochondrial area decreases significantly, and immature eosinophils undergo mitophagy for mitochondrial clearance.*
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- As eosinophils mature, mitochondrial structures change, including increased cristae numbers; inflammation from asthma and schistosomiasis enhances cristae, whereas IAV infection does not significantly alter mitochondrial mass.*
