Publications by authors named "Bruno Koshin Vazquez Iha"
Bacteriophages are recognized as the most abundant members of microbiomes and have therefore a profound impact on microbial communities through the interactions with their bacterial hosts. The International Metagenomics and Metadesign of Subways and Urban Biomes Consortium (MetaSUB) has sampled mass-transit systems in 60 cities over 3 years using metagenomics, throwing light into these hitherto largely unexplored urban environments. MetaSUB focused primarily on the bacterial community.
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- The development of vHULK, a program for predicting bacteriophage hosts, leverages 9504 phage genome features using neural networks.
- The program showed promising results, achieving average precision and recall rates of 83% and 79% at the genus level, and 71% and 67% at the species level in controlled tests.
- Comparative analysis indicates that vHULK outperformed three existing tools in predicting hosts for a set of 2153 phage genomes, marking a significant improvement in phage host prediction technology.