Cognitive impairment, endothelial biomarkers and mortality in maintenance haemodialysis patients: a prospective cohort study.

Background: Haemodialysis (HD) patients have a high prevalence of cardiovascular disease risk factors as well as cognitive impairment. The objective of the present study was to evaluate the interrelationship between cognitive impairment, endothelium-related biomarkers and cardiovascular/non-cardiovascular mortality.

Methods: A total of 216 outpatients were recruited from three centres in a dialysis network in Brazil between June 2016 and June 2019.

Kinetic estimated glomerular filtration rate in critically ill patients: beyond the acute kidney injury severity classification system.

Background: Although significant advances have been achieved in acute kidney injury (AKI) research following its classification, potential pitfalls can be identified in clinical practice. The nonsteady-state (kinetic) estimated glomerular filtration rate (KeGFR) could add clinical and prognostic information in critically ill patients beyond the current AKI classification system.

Methods: This was a retrospective analysis using data from the Multiparameter Intelligent Monitoring in Intensive Care II project.