Publications by authors named "Bruno Flaissier"

Article Synopsis
  • The study investigates the prevalence and risk factors for pneumococcal carriage in cases of influenza-like illness (ILI) in Vientiane, Laos, revealing a significant carriage rate of 16.6%, especially in children under 5 years.
  • Active surveillance involved 5,690 participants from randomly selected households, with data collected through nasopharyngeal swabs and questionnaires over a four-year period.
  • Findings show that pneumococcal carriage is associated with factors like exposure to cigarette smoke and other pathogens, while also highlighting a decline in PCV13 serotypes among young children after the vaccine's introduction in 2013.
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Background: In the Lao People's Democratic Republic (Lao PDR), cervical cancer is the third leading cause of women cancer.

Aims: The objective of this cross-sectional study was to compare the efficacy of careHPV™ test versus conventional Pap smear or Siriraj liquid-based cytology in the detection of cervical cancer in women living with human immunodeficiency virus type 1 (HIV-1).

Materials & Methods: Overall, 631 women consented to participate.

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Article Synopsis
  • Respiratory diseases significantly impact health in tropical nations like Lao PDR, yet there's limited knowledge about viral or bacterial causes of influenza-like illness (ILI) at the community level.
  • A community-based study tracked ILI cases in Vientiane over a year, involving 995 households and 4,885 participants, using various testing methods to identify pathogens.
  • The findings revealed a high incidence of ILI (10.7 episodes per 100 person-years) linked to factors such as age, sex, and living conditions, with common pathogens including Streptococcus pneumoniae and influenza A; co-infections were noted in 24% of cases.
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Objective: To assess 2009 A(H1N1) seroconversion rates and their determinants within an unvaccinated population in Vientiane Capital, Laos.

Methods: CoPanFlu Laos, a general population cohort of 807 households and 4,072 participants was established in March 2010. Sociodemographic data, epidemiological data, and capillary blood samples were collected from all the household members in March, and again in October 2010, in order to assess the level of antibodies to 2009 A(H1N1) with the haemagglutination inhibition assay.

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