A 41-year-old man with recent HIV diagnosis presented with severe symptoms including fever, skin lesions, and confusion, leading to septic shock and multiorgan dysfunction due to AIDS-related disseminated histoplasmosis.
Despite initial concerns, he received a timely diagnosis involving Histoplasma spp. and progressed to intensive care treatment that included antifungal therapy and necessary life support measures.
Ultimately, after 32 days in the ICU and a comprehensive management plan, he improved and was discharged on oral medications, underscoring the importance of recognizing histoplasmosis in advanced HIV patients.