Publications by authors named "Bruno Caldin Silva"

Article Synopsis
  • Point-of-care ultrasonography (POCUS) is becoming essential in critical care because it allows for rapid decision-making without needing to transfer patients out of the ICU, reducing risks and delays.* -
  • While CT scans are still standard for many conditions, POCUS enhances the safety of invasive procedures in the ICU, such as placing vascular catheters and draining fluid collections.* -
  • In nephrology, POCUS provides valuable diagnostic insights for acute kidney injury, helping to quickly rule out conditions like hydronephrosis and gather crucial hemodynamic information for personalized treatment.*
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Article Synopsis
  • High-risk surgical patients often face poor outcomes due to acid-base disorders, specifically metabolic acidosis, which can be assessed using the delta anion gap to bicarbonate ratio.* -
  • This study aimed to evaluate the relationship between metabolic acidosis (MA) and complications in patients undergoing high-risk surgeries by categorizing them into three groups based on their delta AG/delta Bic values.* -
  • Results showed that out of 621 patients, a significant portion had acidosis, and those in the subgroup with no mixed disorders had a notably higher risk of 30-day mortality and cardiovascular complications.*
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Objective: To describe clinical characteristics, resource use, outcomes, and to identify predictors of in-hospital mortality of patients with COVID-19 admitted to the intensive care unit.

Methods: Retrospective single-center cohort study conducted at a private hospital in São Paulo (SP), Brazil. All consecutive adult (≥18 years) patients admitted to the intensive care unit, between March 4, 2020 and February 28, 2021 were included in this study.

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Sleep apnea (SA), a condition associated with increased cardiovascular risk, has been traditionally associated with obesity and aging. However, in patients with fluid-retaining states, such as congestive heart failure and end-stage renal disease, both prevalence and severity of SA are increased. Recently, fluid shift has been recognized to play an important role in the pathophysiology of SA, since the fluid retained in the legs during the day shifts rostrally while recumbent, leading to edema of upper airways.

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Background: Restless leg syndrome (RLS) is a sleep disorder with high prevalence among patients on hemodialysis. It has been postulated that high phosphate and high parathyroid hormone may be implicated in its pathogenesis. Standard international criteria and face-to-face interview are not always applied.

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Study Objectives: Obstructive sleep apnea (OSA) and hypertension are independently associated with increased stiffness of large arteries that may contribute to left ventricular (LV) remodeling. We sought to investigate the impact of OSA, hypertension, and their association with arterial stiffness and heart structure.

Design: We studied 60 middle-aged subjects classified into four groups according to the absence or presence of severe OSA with and without hypertension.

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