Temporal Pattern and Spatial Distribution of Tuberculosis Prevalence Associated with Multimorbidity in Brazil.

Background: Four main chronic conditions may be involved in the tuberculosis pathogenic process and/or clinical evolution: HIV/AIDS, diabetes mellitus, mental illness, and Chronic Obstructive Pulmonary Disease. This study aimed to determine the spatiotemporal pattern of tuberculosis (TB) associated with multimorbidity in Brazil.

Methods: Ecological study use data from the Notifiable Diseases Information System (SINAN), collected from the electronic portal of the Department of Informatics of the SUS (DATASUS).

Clinical outcomes and quality of life of COVID-19 survivors: A follow-up of 3 months post hospital discharge.

Background: Over 66 million people worldwide have been diagnosed with COVID-19. Therefore, understanding their clinical evolution beyond hospital discharge is essential not only from an individual standpoint, but from a populational level.

Objectives: Our primary aim was to assess the impact of COVID-19 on health-related quality of life (HRQoL) 3 months after hospital discharge.

Type 2 diabetes mellitus alters cardiac mitochondrial content and function in a non-obese mice model.

Type 2 diabetes mellitus (T2DM) is associated with an increase of premature appearance of several disorders such as cardiac complications. Thus, we test the hypothesis that a combination of a high fat diet (HFD) and low doses of streptozotocin (STZ) recapitulate a suitable mice model of T2DM to study the cardiac mitochondrial disturbances induced by this disease. Animals were divided in 2 groups: the T2DM group was given a HFD and injected with 2 low doses of STZ, while the CNTRL group was given a standard chow and a buffer solution.

Using Digital Technique to Obtain the Ideal Soft Tissue Contour in Immediate Implants With Provisionalization.

This paper presents a newly developed digital technique to make a provisional crown that mimics the natural tooth during immediate implant placement. Basically, a digital technique results in a precise transfer tooth emergence profile for provisional restoration in immediate implant placement so that an ideal periimplant soft tissue contour can be maintained. The architecture of extraction socket is obtained digitally before the surgery that allows for implant planning by position of the implant as well as the emergence profile of provisional restoration.