Publications by authors named "Bruno Brandimarte"
Article Synopsis
- SARS-CoV-2 is recognized as one of the most significant pandemics in recent history, prompting a search for effective non-biological antiviral treatments.
- Researchers are focusing on repurposing existing drugs and have identified key host factors, such as the molecular chaperone GRP78, that facilitate the virus's entry into cells.
- TL1228, a small molecule found through in silico screening, inhibits the interaction between SARS-CoV-2 and GRP78, significantly reducing viral activity and influencing immune response and inflammation markers in lab studies.
The currently available nebulization devices have a slow aerosol flow and produce vapor with large microdrops. Improved devices that achieve higher airflow and produce smaller microdrops are needed to improve the clinical care of patients. To address this critical need, we developed a novel system for the molecular vaporization of liquids.
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