Publications by authors named "Bruno Branciforte"

Article Synopsis
  • Hepatocellular carcinoma (HCC) has a poor prognosis, and this study examines the effectiveness of neoadjuvant transarterial chemoembolization (TACE) for large, resectable HCC tumors over 5 cm.
  • In a retrospective analysis of 384 patients, TACE showed no significant impact on disease-free survival or overall survival when compared to surgery alone, even after adjusting for other variables.
  • However, TACE may benefit specific patients, particularly those with very large tumors (≥10 cm), single tumors, or those needing portal vein embolization.
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Background: Segmental or subsegmental anatomical resection (AR) of hepatocellular carcinoma (HCC) in minimal access liver surgery (MALS) has been technically proposed. The Glissonean approach or dye injection technique are generally adopted. The tumor-feeding portal pedicle compression technique (C-AR) is an established approach in open surgery, but its feasibility in the MALS environment has never been described.

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Article Synopsis
  • Patients with colorectal liver metastases near the hepatic vein often undergo major surgeries, but parenchyma-sparing laparoscopy techniques show promise.
  • A patient who had a tumor in contact with the middle and left hepatic veins received a limited liver resection using careful surgical techniques to minimize damage.
  • The surgery was successful with minimal blood loss and a short recovery time, indicating that laparoscopic methods can be a viable alternative to more invasive procedures.
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Background: Deep-located liver tumors involving hepatic veins at the caval confluence or main Glissonean pedicles generally require a major hepatectomy. An intraoperative ultrasound guidance policy opened a possibility to opt for parenchyma-sparing procedures as alternatives to major hepatectomy, called transversal hepatectomies. We ought to standardize the procedure and analyze the surgical outcome, oncological suitability, and salvageability.

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Background: Despite survival improvements for other cancers, the prognosis of resected mass-forming cholangiocellular carcinoma (MFCCC) remains dismal. As a possible background of that, biologic factors could play some role. KRAS mutation has been investigated in the present systematic review and meta-analysis.

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Background: The American College of Surgeons National Surgical Quality Improvement Program's (ACS-NSQIP) calculator has been endorsed to counsel patients regarding complications. The aim of this study was to assess its ability to predict outcomes after hepatectomy.

Methods: Outcomes generated by the ACS-NSQIP were recorded in a consecutive cohort of patients.

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Background: Recent evidence suggests that gadolinium ethoxybenzyl diethylenetriamine penta acetic acid-enhanced (Gd-EOB-DTPA) magnetic resonance imaging may be used to evaluate liver function. The aim of this study was to assess whether the signal intensity of Gd-EOB-DTPA magnetic resonance imaging may be used to predict functional liver reserve and posthepatectomy liver failure in patients undergoing hepatectomy for liver tumors.

Methods: This is an observational retrospective study on 137 preoperative Gd-EOB-DTPA magnetic resonance imaging of patients undergoing hepatectomy between 2015 and 2018.

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Background: Anatomical resection (AR) is a recommended surgical treatment for hepatocellular carcinoma (HCC), although the conventional procedure (dye injection) for AR is difficult to reproduce.1,2 The tumor-feeding portal pedicle compression technique has been proposed as an easy, reversible, repeatable, and oncologically suitable procedure,3-5 and its only drawback is the sometimes faint discoloration of the compressed area. For enhancing its visibility, indocyanine green (ICG) fluorescence imaging has been introduced.

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