Publications by authors named "Bruno Barauna da Silva"
Article Synopsis
- * Different concentrations of L-arginine (0, 1, 10, and 50 mM) were tested for their impact on fertilization rates, the production of nitric oxide, cleavage, blastocyst rates, and total blastocyst cell numbers over time.
- * The results showed that while high concentrations (50 mM) of L-arginine harmed embryo development, a lower concentration (1 mM) with Bos indicus sperm improved the rate of hatched blastocysts, suggesting that too much L
Supplementation of bovine embryo culture medium with L-arginine improves embryo quality via nitric oxide production.
Priscila Di Paula Bessa Santana Thiago Velasco Guimarães Silva Nathália Nogueira da Costa Bruno Barauna da Silva Timothy Frederick Carter Marcela da Silva Cordeiro Bruno José Martins da Silva
Mol Reprod Dev
October 2014
Nitric oxide (NO) is a cell-signaling molecule that regulates a variety of molecular pathways. We investigated the role of NO during preimplantation embryonic development by blocking its production with an inhibitor or supplementing in vitro bovine embryo cultures with its natural precursor, L-arginine, over different periods. Endpoints evaluated included blastocyst rates, development kinetics, and embryo quality.
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