Publications by authors named "Bruno Araujo Souza"
Article Synopsis
- GP63, a key surface protease of Leishmania spp., is crucial for the parasite's virulence and may serve as a target for future vaccines.
- The study analyzes the genetic variability of gp63 in Leishmania (Viannia) braziliensis from two groups of cases in Brazil, revealing extensive polymorphism with 45 different alleles identified.
- Despite high genetic variability among isolates, regions of gp63 responsible for interactions with host cells are highly conserved, indicating a potential area for vaccine development.
