Increase of the glycolytic rate in human resting fibroblasts following serum stimulation. The possible role of the fructose-2,6-bisphosphate.

We report that glycolysis in human quiescent fibroblasts stimulated by serum addition is increased, and that the changes of the metabolic route reflect the activity of the phosphofructokinase. A possible role of fructose-2,6-bisphosphate as a positive modulator of the key enzyme is proposed.

[Right temporo-occipital ganglioglioma in a 10-year-old patient].

Authors describe an operated case of ganglioglioma of the right temporo-occipital region in a ten year old patient. After case presentation and an analysis of the literature, the diagnostic pre-operative problems are discussed analysing the CT aspects of the lesion.

Relaxin in human decidua.

Relaxin (RLX) has been purified from the ovary of the pregnant pig and rat but not from human tissues. Our study shows that tissue extracts and incubation media of in vitro culture of human decidua contain a substance with relaxin bioactivities: the inhibition of spontaneous uterine contractions and the elongation of the interpubic ligament. After chromatography on Sephadex G-50 the bioactivity was retained in a protein fraction of approximately 6000 daltons mol wt.

Trace element determination-I Use of 2,9-dimethyl-1,10-phenanthroline in determination of copper in heavy matrices by carbon furnace atomic-absorption spectrometry.

A method for the determination of copper in complex matrices by electrothermal atomic-absorption spectrometry has been developed. It uses neocuproine as complexing agent. The detection limit is 0.

Unusual evolution of a post-traumatic subdural haematoma. Case report.

The authors describe a case of a post-traumatic subdural haematoma with an unusual evolution in two phases, one slow, the other very rapid. The rapidity of the evolution was caused by the rupture of a cortical dural artery, shown angiographically.

Some properties of glucose-6-phosphate dehydrogenase from rat and chick brain: a comparative study.

1. Glucose-6-phosphate dehydrogenase (G6PDH) has been purified to homogeneity from rat and chick brain by affinity chromatography with Sepharose bound 2',5' ADP. 2.

Effect of prostaglandins in vivo on enzymes involved in thyroid carbohydrate metabolism.

Treatment of adult guinea pigs with prostaglandins produces changes in the levels of enzymes involved in carbohydrate metabolism of the thyroid gland. A decrease in glucose-6-phosphate dehydrogenase activity is observed with a concomitant increase in 6-phosphogluconic dehydrogenase; the glycolytic enzymes appear unaffected by the same treatment. The results indicate that prostaglandins do not have the biochemical effects obtained with thyrotropin and cAMP administration, showing that these compounds play an antagonistic role in comparison with the above mentioned stimulating agents.