Spinning gold: Unraveling the bioaccessibility and bioavailability of Pitanga's carotenoid microfibers.

The design and development of nanoparticle- and microparticle-based delivery systems incorporating carotenoids into carrier materials offers multiple advantages, including enhancing the bio-efficacy of these compounds due to improving their bioaccessibility and bioavailability. This study introduced pitanga saponified carotenoid extract (PSCE) and pitanga non-saponified carotenoid extract (PSCE) in a 12 % zein/1 %PEO solution and electrospun for fiber production. Then, the fibers were characterized, and their bioaccessibility and bioavailability were also evaluated.

Bioaccessibility and Cellular Uptake of Carotenoids Extracted from Fruit: Differences between Conventional and Ionic Liquid-Mediated Extraction.

Currently, on an industrial scale, synthetic colorants are used in many fields, as well as those extracted with conventional organic solvents (COSs), leading to several environmental issues. Therefore, we developed a sustainable extraction and purification method mediated by ionic liquids (IL), which is considered an alternative high-performance replacement for COSs. Carotenoids are natural pigments with low bioaccessibility (BCT) and bioavailability (BV) but with huge importance to health.

Bioaccessibility and cellular uptake by Caco-2 cells of carotenoids and chlorophylls from orange peels: A comparison between conventional and ionic liquid mediated extractions.

Native extracts from orange peels were obtained by a conventional method using acetone and, an alternative method using ionic liquid (1-butyl-3-methylimidazolium chloride ([Cmim]Cl)). The bioaccessibilities and cellular uptakes of carotenoids, esters and chlorophylls were evaluated, since the influence of esterification on bioaccessibility and bioavailability is not well established. For this, the extracts were emulsified, submitted to in vitro simulated digestion model according to the INFOGEST protocol, followed by uptake by Caco-2 cells.

Brazilian Biodiversity Fruits: Discovering Bioactive Compounds from Underexplored Sources.

Large segments of the Brazilian population still suffer from malnutrition and diet-related illnesses. In contrast, many native fruits have biodiversity and are underexploited sources of bioactive compounds and unknown to consumers. The phytochemical composition of nine underexplored Brazilian fruits was determined.