Publications by authors named "Bruna Schwengber Lutz"
Activity of ecto-5'-nucleotidase (NT5E/CD73) is increased in papillary thyroid carcinoma and its expression is associated with metastatic lymph nodes.
Ana Paula Santin Bertoni Paula Andreghetto Bracco Rafael Paschoal de Campos Bruna Schwengber Lutz Beatriz Maria Assis-Brasil
Mol Cell Endocrinol
January 2019
Article Synopsis
- The study investigates the role of the NT5E gene in papillary thyroid carcinoma (PTC) and its potential as a therapeutic target.
- Significant differences in AMP hydrolysis and NT5E expression were found between PTC cells and normal thyroid cells, indicating a potential link to tumor progression.
- Higher NT5E levels correlated with clinical features like larger tumor size and the presence of metastatic lymph nodes in PTC patients.