Publications by authors named "Bruna Ramos Silva"

Purpose: Metabolic diseases such as diabetes mellitus may play a role in the development and progression of prostate cancer (PC); however, this association remains to be explored in the context of specific PC stages. The objective of this study was to systematically review the evidence for an association between diabetes and overall, early, or advanced PC risk.

Materials And Methods: A systematic review with meta-analysis was performed (MEDLINE, EMBASE, and CINAHL) from inception until September 2023.

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  • The study examined the relationship between phase angle (PhA) and health-related physical fitness in older breast cancer survivors who underwent chemotherapy.
  • PhA was measured using bioelectrical impedance analysis (BIA), and the research involved 22 women aged 60+ who also participated in cardiopulmonary exercise tests and MRI scans.
  • Results indicated that higher PhA correlates with improved cardiorespiratory fitness, greater skeletal muscle volume, and lower myosteatosis, suggesting better overall muscle health in this population.
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  • This study analyzed the effects of an 8-week time-restricted eating (TRE) intervention on body composition in women over 60 who had completed chemotherapy for early-stage breast cancer.
  • Results showed significant reductions in body weight and total fat mass, while most participants exhibited low phase angles indicating poorer cell health and hydration issues.
  • The findings suggest that TRE can lead to improved body composition metrics in obese participants, highlighting the usefulness of bioelectrical impedance vector analysis (BIVA) for assessing these changes.
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Phase angle is a composite measure that combines two raw bioelectrical impedance analysis measures: resistance and reactance. Phase angle has been considered an indicator of cellular health, integrity, and hydration. As inflammation and oxidative stress can damage cellular structures, phase angle has potential utility in early detecting inflammatory and oxidative status.

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Nutritional status can change in breast cancer patients after treatment. However, the metabolic implications of those alterations are poorly understood. We used a cross-sectional study design to compare body composition, lipids, glucose levels, and adiposity indices in breast cancer patients with a matched control and a healthy group.

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Chronic conditions including non-communicable diseases have become increasingly prevalent in the past decade. Proinflammatory cytokines are associated with the development of several pathologies, their prognoses, and their associated mortality. Chronic inflammation is also associated with oxidative stress whereby reactive oxygen species (ROS) induce cellular injury and, thus, by doing so, initiate inflammatory signaling.

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Objective: The aim of this study was to evaluate the applicability of phase angle (PhA) as a severity indicator of chronic liver diseases.

Methods: We examined the medical records of 54 patients-27 with hepatocellular carcinoma (HCC) and 27 with non-alcoholic fatty liver disease (NAFLD). The patients were ≥18 y of age.

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Objectives: Dietary omega-3 fatty acids have been efficacious in decreasing serum cholesterol levels and reducing the risk of cardiovascular disease. However, the metabolic and molecular changes induced by the omega-3 fatty acid α-linolenic acid (ALA), which is found in linseed oil, are not fully understood. In this study, we showed a correlation between ALA and insulin resistance, inflammation and endoplasmic reticulum stress (ERS).

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  • A study aimed to evaluate the accuracy of several body fat measurement indices, including BMI and its adjusted forms, comparing them to bioelectrical impedance and DXA among a Brazilian population of 240 hospitalized patients.
  • The participants included 43 men and 197 women, with similar average ages around 53 years, and the findings indicated a high prevalence of excess weight across the different indices.
  • The BMIfat showed the strongest correlation with DXA results, suggesting it is the most reliable index for predicting body fat, while BAI was less effective than BMI; further research is recommended to support these conclusions.
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Objective: To compare the diagnostic performance of adiposity indeces body mass index (BMI), body mass index adjusted for fat mass (BMIfat), body adiposity index (BAI) and body adiposity index for the Fels Longitudinal Study sample (BAIFels) and the overweight detection in a sample of the Brazilian population.

Methods: Cross-sectional study with 501 individuals (female/male = 387/114), which underwent anthropometric measurements and body composition for subsequent calculation of adiposity indices. Statistical analyzes considered p < 0.

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Metabolism disorders, as well as body shape abnormalities, have been associated with the introduction of antiretroviral therapy. The objective of this study was to compare the diagnostic ability of adiposity indices and to discuss criteria for the classification of lipodystrophy and sarcopenia (SP) in HIV-positive individuals. Anthropometric measurements were determined in 268 individuals of both genders, also submitted to the dual-energy X-ray absorptiometry exam.

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Background: Highly active antiretroviral therapy (HAART) can cause side effects in HIV patients, as the metabolic syndrome. Early identification of risk for development of cardiovascular diseases using available reliable and practical methods is fundamental. On this basis, the aim of this study was to compare the effectiveness of anthropometric indicators to identify metabolic syndrome in HIV patients on HAART.

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