Publications by authors named "Bruce E Ruck"

Article Synopsis
  • This study reviewed opioid exposures in young children, specifically looking at data from America's Poison Centers® between 2016 and 2023, to assess the impact of fentanyl and medications for opioid use disorder.
  • Out of 34,632 reports, most exposures (96.7%) were unintentional, with a median age of exposure being 2 years. While overall reported exposures decreased by 57.5%, there was a concerning 300% increase in deaths and major effects.
  • The study emphasizes the importance of improving poisoning prevention strategies, as medications like buprenorphine and methadone showed a significant association with severe effects, alongside rising cases of fentanyl and heroin exposure.
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Background: Opioid-associated ototoxicity is a known complication of opioid exposure, although the mechanism remains unclear. While historically most closely linked to heroin and oxycodone, evolving reports suggest that it may be a class effect of opioids. However, the evidence is limited to case reports.

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Bismuth subsalicylate (BSS) is the active ingredient in over-the-counter antacid and antidiarrheal medications. Coagulopathy in the setting of acetylsalicylic acid toxicity is well documented but not in setting of bismuth subsalicylate overuse. We present a case report of coagulopathy from BSS poisoning in a patient with underlying cirrhosis.

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