Publications by authors named "Brown Chiwandira"

Viral suppression (VS) in children has remained suboptimal compared to that in adults. We evaluated the impact of transitioning children weighing < 20 kg to a pediatric formulation of dolutegravir (pDTG) on VS in Malawi. We analyzed routine retrospective program data from electronic medical record systems pooled across 169 healthcare facilities in Malawi supported by the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF).

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Background: Despite tremendous progress in antiretroviral therapy (ART) and access to ART, many patients have advanced human immunodeficiency virus (HIV) disease (AHD). Patients on AHD, whether initiating ART or providing care after disengagement, have an increased risk of morbidity and mortality. The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) launched an enhanced care package using a hub-and-spoke model to optimize AHD care in Malawi.

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Article Synopsis
  • The Malawi Ministry of Health and Médecins sans Frontières have been working together since 2011 to improve access to HIV care by decentralizing antiretroviral therapy from hospitals to local clinics in Nsanje District.
  • A household survey was conducted from September 2016 to January 2017, where participants aged 15 and older were tested for HIV, and those who tested positive had their viral load measured.
  • The results showed a 12.1% HIV prevalence in the surveyed population, with higher rates in women, and indicated strong awareness of HIV status (80%) and linkage to care (78%), with 95.3% of those aware receiving ART.
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Background: To assist the Malawi Ministry of Health to evaluate 2 competing strategies for scale-up of isoniazid preventive therapy (IPT) among HIV-positive adults receiving antiretroviral therapy.

Setting: Malawi.

Methods: We used a multidistrict, compartmental model of the Malawi tuberculosis (TB)/HIV epidemic to compare the anticipated health impacts of 6-month versus continuous IPT programs over a 12-year horizon while respecting a US$10.

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