Reemergence of Bordetella parapertussis, United States, 2019-2023.

To determine changes in Bordetella pertussis and B. parapertussis detection rates, we analyzed 1.43 million respiratory multiplex PCR test results from US facilities from 2019 through mid-2023.

The epidemiology of pediatric outpatient acute respiratory tract infections in the US: a multi-facility analysis of multiplex PCR testing from 2018 to 2023.

Post-pandemic, it is essential to understand the epidemiology of pediatric acute respiratory tract infections (ARTIs). Our multi-facility study elucidates the outpatient epidemiology of pediatric ARTI using highly multiplexed PCR testing, providing critical insights into the evolving landscape of the etiological agents with a particular focus on the years following the emergence of SARS-CoV-2. Utilizing data from two different multiplex PCR panels, our research provides a comprehensive analysis of respiratory pathogen positivity from 2018 to 2023.

rates in blood culture on the rise: results of US surveillance.

is an emerging pathogen that poses a significant public health risk. Its multidrug resistance has led to high mortality, making rapid detection crucial for effective treatment and prevention of transmission. Recent data from the Centers for Disease Control and Prevention indicate a substantial increase in cases in the United States, with a 95% rise in 2021.

Polymer Spreading on Unidirectionally Nanotextured Substrates Using Molecular Dynamics.

A unidirectional nanotexture alters the wettability of a substrate and can be used to create patterned polymer films, tailored polymer coverage/reflow, or aligned polymer molecules. However, the physical mechanisms underlying polymer spreading on nanoscale textures are not well-understood, and competing theories exist to explain how texture peaks and grooves alter the wettability of a substrate. We use molecular dynamics to simulate polymer spreading on substrates with unidirectional nanoscale textures as a function of texture shape and size and compare to polymer spreading on a flat substrate.

Polymer spreading on substrates with nanoscale grooves using molecular dynamics.

Understanding how liquid polymer interacts with and spreads on surfaces with nanoscale texture features is crucial for designing complex nanoscale systems. We use molecular dynamics to simulate different types of polymer as they spread on substrates with a single nanoscale groove. We study how groove design affects the potential energy of a substrate and how this governs polymer spreading and orientation.

Spreading Kinetics of Ultrathin Liquid Films Using Molecular Dynamics.

Ultrathin liquid films play a critical role in numerous engineering applications. Although crucial to the design and application of ultrathin liquid films, the physical mechanisms that govern spreading on the molecular scale are not well-understood, and disagreement among experiments, simulations, and theory remains. We use molecular dynamics simulations to quantify the speed at which the edge of a polymer droplet advances on a flat substrate as a function of various environmental and design parameters.