Aspirin rechallenge in an adult patient previously diagnosed with Reye syndrome.

Purpose: Aspirin has been the cornerstone of antiplatelet therapy in patients with acute coronary syndromes and is well accepted and recommended by several major healthcare organizations. A combination of aspirin and a P2Y12 inhibitor, commonly known as dual antiplatelet therapy, is recommended in patients with coronary stent implantation to reduce the risk of stent thrombosis and ischemic events.

Summary: We recently cared for an adult male who presented with an acute coronary syndrome who had a history of Reye syndrome during childhood.