Not All Fun and Games: A Case Report of Contact Dermatitis Related to Slime and Play-Doh.

Slime and Play-Doh have been gaining popularity among adolescents and preteens. Both are gooey, viscoelastic substances that can be morphed and molded into virtually anything imaginable. Slime can be made from several household products including school glue and borax, which have both been linked to cases of irritant and allergic contact dermatitis, conditions that historically involve activation of many immune-regulatory cells such as Langerhans' cells and T cells.

Treatment Changes in Patients With Moderate to Severe Psoriasis: A Retrospective Chart Review.

Background: Psoriasis treatment involves topical medications, oral medications, phototherapy, and/or biologics. The treatments used depend on a myriad of factors that change over time.

Objective: To characterise the frequency of and reasons for treatment changes in patients with moderate to severe psoriasis.

Most people with psoriasis or rosacea are not being treated: a large population study.

When left untreated, psoriasis and rosacea can have long-term health and psychosocial implications. The purpose of this study was to estimate the percentage of Americans with psoriasis or rosacea who are not being treated. Patient data from a large claims-based database were analyzed to identify the number of patients who are treated for psoriasis or rosacea.

The cost-effectiveness of ustekinumab for moderate-to-severe psoriasis.

Given its chronicity and impact on quality of life, psoriasis is a costly disease. As new and better treatments are developed, the cost of treating psoriasis has risen. In this drug profile, the authors discuss ustekinumab, its pharmacokinetics, safety profile, and direct and indirect costs to determine its cost-efficacy.