Publications by authors named "Brooke P Lichak"

Background Television and media have a profound effect on viewers' understanding and interpretation of the world we live in. Reality television can be even more influential to viewers given its depiction of "real life". Materials and methods Every episode (n=46) was analyzed from five medical reality television shows.

View Article and Find Full Text PDF

Concussion is a heterogeneous injury that relies predominantly on subjective symptom reports for patient assessment and treatment. Developing an objective, biological test could aid phenotypic categorization of concussion patients, leading to advances in personalized treatment. This prospective multi-center study employed saliva micro-ribonucleic acid (miRNA) levels to stratify 251 individuals with concussion into biological subgroups.

View Article and Find Full Text PDF

Cefepime is a renally excreted, fourth-generation cephalosporin used in the treatment of severe abdominal, skin, soft tissue, and urinary tract infections due to its broad-spectrum coverage. Cefepime-induced neurotoxicity is a rare but serious side effect that has increased in recent years likely due to increased antibiotic use, increased drug resistance, and increased symptom recognition. While decreased glomerular filtration rate is an important risk factor for developing elevated serum cefepime levels, recent literature has suggested that a significant proportion of patients with normal renal function can also develop neurotoxicity from cefepime.

View Article and Find Full Text PDF

The annotation of six cluster N phages (Kevin1, Nenae, Parmesanjohn, ShrimpFriedEgg, Smurph, and SpongeBob) reveals regions of genomic diversity, particularly within the central region of the genome. The genome of Kevin1 includes two orphams (genes with no similarity to other phage genes), with one predicted to encode an AAA-ATPase.

View Article and Find Full Text PDF
Article Synopsis
  • - Mycobacteriophages Chancellor, Mitti, and Wintermute infect the bacterial strain mc155 and belong to subcluster K4, sharing close relationships with phages Cheetobro and Fionnbharth.
  • - These phages have genome sizes that vary between 57,697 bp and 58,046 bp.
  • - They are predicted to be temperate, meaning they can integrate into the host's genome, and they specifically target a pathogen.
View Article and Find Full Text PDF