Publications by authors named "Brooke E Pierson"

Article Synopsis
  • ECMO usage is increasing, but determining which patients will benefit the most is challenging, making risk stratification crucial.
  • This study evaluated the impact of two biomarkers, SDC-1 and soluble thrombomodulin (sTM), on mortality rates in patients on venoarterial ECMO.
  • Results showed that higher levels of sTM significantly correlate with increased mortality risk, while SDC-1 levels are marginally predictive; these findings suggest that incorporating these biomarkers could enhance existing scoring systems for better patient assessment.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of combining autologous skin cell suspension (ASCS) with meshed split-thickness skin grafts (mSTSG) for treating large burns, aiming to improve healing times and reduce aesthetic issues.
  • Experiments conducted on pigs showed that wounds treated with ASCS had significantly faster re-epithelialization rates compared to those without ASCS, particularly noted on days 3, 5, and 7 post-grafting.
  • However, despite the improved healing rates, the presence of ASCS did not affect the patterning of the scars, indicating that while ASCS enhances healing, it may not address visual scarring issues.
View Article and Find Full Text PDF